Esr2 - estrogen receptor 2 (beta) Gene

中文名称：雌激素受体 2 (β)

种属: Mus musculus

同用名: ER[b]; Estrb; ERbeta

关于 Esr2

功能概要

该基因编码的蛋白可启动 DNA 结合活性。作用于几个过程的上游或内部，包括激素介导的信号通路；神经系统发育；和生殖结构发育。位于细胞质和细胞核中。以多种结构表达，包括中枢神经系统；泌尿生殖系统；心脏肠系膜；肢体部分；和乳腺原基。该基因的人类直系同源物与多种疾病有关，包括动脉疾病（多种）；自身免疫性疾病（多种）；尿道下裂;神经退行性疾病（多种）；和卵巢发育不全 8。与人类 ESR2（雌激素受体 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables DNA binding activity. Acts upstream of or within several processes, including hormone-mediated signaling pathway; nervous system development; and reproductive structure development. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; heart mesentery; limb segment; and mammary gland primordium. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); hypospadias; neurodegenerative disease (multiple); and ovarian dysgenesis 8. Orthologous to human ESR2 (Estrogen Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]