Bmpr2 - bone morphogenetic protein receptor type 2 Gene

中文名称：骨形态发生蛋白受体 2 型

种属: Rattus norvegicus

同用名: Bmpr-II

关于 Bmpr2

功能概要

该基因编码的蛋白可启动生长因子结合活性。参与相机型眼的大脑发育和视网膜发育。位于几种细胞成分中，包括顶端质膜；基底质膜；和小窝。用于研究肺动脉高压。肺动脉高压的生物标志物。该基因的人类直系同源物与心脏间隔缺损有关；原发性肺动脉高压;肺动脉高压;和肺静脉闭塞性疾病。与人类 BMPR2（骨形态发生蛋白受体 2 型）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables growth factor binding activity. Involved in brain development and retina development in camera-type eye. Located in several cellular components, including apical plasma membrane; basal plasma membrane; and caveola. Used to study pulmonary hypertension. Biomarker of pulmonary hypertension. Human ortholog(s) of this gene implicated in heart septal defect; primary pulmonary hypertension; pulmonary hypertension; and pulmonary venoocclusive disease. Orthologous to human BMPR2 (bone morphogenetic protein receptor type 2). [provided by Alliance of Genome Resources, Apr 2022]