2. Gene
  3. Fkbp1a - FK506 binding protein 1a Gene

Fkbp1a - FK506 binding protein 1a Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fkbp; Fkbp1; FKBP12

基因 ID: 14225 | 基因类型: protein coding

关于 Fkbp1a

功能概要

This gene is a member of the immunophilin family. The encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, and is associated with immunoregulation, protein folding, receptor signaling, protein trafficking and T-cell activation. It may modulate the calcium release activity of the ryanodine receptor Ryr1. It also interacts with the type I TGF-beta Receptor. Disruption of this gene in mouse causes severe ventricular defects. Pseudogenes of this gene have been defined on chromosomes 4, 10, 14, and 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Fkbp1a 基因产物(7)

mRNA Protein Name
NM_001302077.1 NP_001289006.1 peptidyl-prolyl cis-trans isomerase FKBP1A isoform 1
NM_001302078.1 NP_001289007.1 peptidyl-prolyl cis-trans isomerase FKBP1A isoform 2
NM_001302079.1 NP_001289008.1 peptidyl-prolyl cis-trans isomerase FKBP1A isoform 3
NM_001302080.1 NP_001289009.1 peptidyl-prolyl cis-trans isomerase FKBP1A isoform 3
NM_001355077.1 NP_001342006.1 peptidyl-prolyl cis-trans isomerase FKBP1A isoform 2
NM_001355078.1 NP_001342007.1 peptidyl-prolyl cis-trans isomerase FKBP1A isoform 4
NM_008019.3 NP_032045.1 peptidyl-prolyl cis-trans isomerase FKBP1A isoform 1
蛋白主名 其他名称

peptidyl-prolyl cis-trans isomerase FKBP1A

FK506 binding protein 12

PPIase FKBP1A

calstabin-1

immunophilin FKBP12

重组 Fkbp1a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76346 FKBP12 Protein, Mouse (His) P26883 (G2-E108) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04960 FKBP1A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fkbp1a NCBI NCBI:2280
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