2. Gene
  3. LDLRAD3 - low density lipoprotein receptor class A domain containing 3 Gene

LDLRAD3 - low density lipoprotein receptor class A domain containing 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含低密度脂蛋白受体 A 类结构域 3

种属: Homo sapiens

同用名: LRAD3

基因 ID: 143458 | 基因类型: protein coding

关于 LDLRAD3

Cytogenetic location: 11p13 Genomic coordinates (GRCh38): 11:35,944,062-36,232,136 (from NCBI)

This gene has 6 transcripts (splice variants) and 168 orthologues. Ubiquitous expression in brain (RPKM 8.5), prostate (RPKM 7.2) and 25 other tissues.

功能概要

预测启用淀粉样蛋白-β 结合活性。预计在受体介导的内吞作用和蛋白质加工调节的上游或内部起作用。预测位于膜中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable amyloid-beta binding activity. Predicted to act upstream of or within receptor-mediated endocytosis and regulation of protein processing. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

LDLRAD3 基因产物(3)

mRNA Protein Name
NM_001304263.2 NP_001291192.1 low-density lipoprotein receptor class A domain-containing protein 3 isoform 2 precursor
NM_001304264.2 NP_001291193.1 low-density lipoprotein receptor class A domain-containing protein 3 isoform 3
NM_174902.4 NP_777562.1 low-density lipoprotein receptor class A domain-containing protein 3 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
26854353 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

LDLRAD3 蛋白结构

Ldl_recept_a

Ldl_recept_a: Low-density lipoprotein receptor domain class A (28 - 64)

Ldl_recept_a

Ldl_recept_a: Low-density lipoprotein receptor domain class A (69 - 106)

Ldl_recept_a

Ldl_recept_a: Low-density lipoprotein receptor domain class A (113 - 147)

  • 0
  • 100
  • 200
  • 300
  • 345 a.a.
蛋白主名 其他名称

low-density lipoprotein receptor class A domain-containing protein 3

LDLR class A domain-containing protein 3

重组 LDLRAD3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77057 LDLRAD3 Protein, Human (HEK293, Fc) Q86YD5-1/NP_777562.1 (Q18-T173) ≥95%

关联疾病

疾病名称 别名
Venezuelan Equine Encephalitis

Venezuelan Equine Fever

Venezuelan Equine Encephalomyelitis

Encephalitis Venezuelan Equine

Encephalomyelitis, Venezuelan Equine

Venezuelan Encephalitis

Disorder Due To Venezuelan Equine Encephalitis Virus

Venezuelan Equine Encephalitis Virus Infection

Venezuelan Equine Encephalomyelitis Virus Disease
Encephalitis

Mumps Encephalitis

Mumps Meningoencephalitis

Herpes Simplex Neuroinvasion

Herpetic Encephalitis

Herpetic Encephalopathy

Herpes Simplex Encephalitis, Myelitis Or Encephalomyelitis

Encephalitis Due To Herpesviridae

Encephalitis Due To Herpesvirus

Herpes Encephalitis

Herpesviral Encephalitis

Herpes Simplex Encephalitis

Hsv - [Herpes Simplex Virus] Encephalitis

Herpes Virus Encephalitis

Simian B Disease

Simian B Disorder

Encephalitis Nec

Idiopathic Encephalitis
Postinflammatory Pulmonary Fibrosis

Post-Inflammatory Pulmonary Fibrosis
Western Equine Encephalitis

Western Equine Encephalomyelitis

Wee

Encephalomyelitis, Western Equine

Western Equine Encephalitis Virus Infection

Wee - [Western Equine Encephalitis]

Western Equine Encephalitis Virus
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07578 LDLRAD3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus LDLRAD3 RGD RGD:1307846
Macaca mulatta LDLRAD3 VGNC VGNC:74137
Felis catus LDLRAD3 VGNC VGNC:82035
Mus musculus LDLRAD3 MGD MGI:2138856
Bos taurus LDLRAD3 VGNC VGNC:30828
Canis familiaris LDLRAD3 VGNC VGNC:42624
Others LDLRAD3 NCBI
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