1. Gene
  2. OR51E1 - olfactory receptor family 51 subfamily E member 1 Gene

OR51E1 - olfactory receptor family 51 subfamily E member 1 Gene

中文名称:嗅觉受体家族 51 亚家族 E 成员 1

种属: Homo sapiens

同用名: POGR; DGPCR; PSGR2; D-GPCR; GPR136; GPR164; OR51E1P; OR52A3P

基因 ID: 143503 | 基因类型: protein coding

关于 OR51E1

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:4,643,982-4,655,488 (from NCBI)

This gene has 2 transcripts (splice variants), 71 orthologues and 51 paralogues. Biased expression in prostate (RPKM 7.2), fat (RPKM 4.9) and 8 other tissues.

功能概要

嗅觉受体与鼻子中的气味分子相互作用,引发神经元反应,从而触发对气味的感知。嗅觉受体蛋白是来自单个编码外显子基因的 G 蛋白偶联受体 (GPCR) 大家族的成员。嗅觉受体与许多神经递质和激素受体共享一个 7 跨膜结构域,负责气味信号的识别和 G 蛋白介导的转导。嗅觉受体基因家族是基因组中最大的。分配给该生物体的嗅觉受体基因和蛋白质的命名法独立于其他生物体。[RefSeq 提供,2008 年 7 月]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory Receptor Proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

OR51E1 基因产物(1)

mRNA Protein Name
NM_152430.4 NP_689643.2 olfactory receptor 5.10E+02
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

OR51E1 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (44 - 294)

  • 0
  • 100
  • 200
  • 300
  • 318 a.a.
蛋白主名 其他名称

olfactory receptor 51E1

Dresden-G-protein-coupled receptor

直系同源

种属 基因名 来源 基因 ID
Mus musculus OR51E1 MGD MGI:3030392
Rattus norvegicus OR51E1 RGD RGD:1332833
Canis familiaris OR51E1 VGNC VGNC:95370
Bos taurus OR51E1 VGNC VGNC:101074