Gfap - glial fibrillary acidic protein Gene

种属: Mus musculus

关于 Gfap

功能概要

A structural constituent of Cytoskeleton. Involved in regulation of chaperone-mediated Autophagy. Acts upstream of or within with a positive effect on D-aspartate import across plasma membrane; gene expression; and intracellular protein transport. Acts upstream of or within several processes, including intermediate filament organization; long-term synaptic potentiation; and neurogenesis. Located in several cellular components, including astrocyte end-foot; cell body; and intermediate filament. Is expressed in several structures, including alimentary system; hemolymphoid system; integumental system; nervous system; and sensory organ. Used to study Alexander disease. Human ortholog(s) of this gene implicated in Alexander disease. Orthologous to human GFAP (glial fibrillary acidic protein). [provided by Alliance of Genome Resources, Apr 2022]