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  2. Lilrb4a - leukocyte immunoglobulin-like receptor, subfamily B, member 4A Gene

Lilrb4a - leukocyte immunoglobulin-like receptor, subfamily B, member 4A Gene

种属: Mus musculus

同用名: HM18; ILT3; gp49; CD85K; Gp49b; LIR-5; Lilrb4

基因 ID: 14728 | 基因类型: protein coding

关于 Lilrb4a

功能概要

Enables Integrin binding activity. Involved in negative regulation of mast cell activation involved in immune response. Acts upstream of or within several processes, including alpha-beta T cell proliferation; cellular response to lipopolysaccharide; and response to nematode. Located in external side of plasma membrane. Is expressed in urinary system. Orthologous to human LILRB4 (leukocyte immunoglobulin like receptor B4). [provided by Alliance of Genome Resources, Apr 2022]

Lilrb4a 基因产物(2)

mRNA Protein Name
NM_001291894.1 NP_001278823.1 leukocyte immunoglobulin-like receptor subfamily B member 4A isoform 2
NM_013532.3 NP_038560.1 leukocyte immunoglobulin-like receptor subfamily B member 4A isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fibronectin binding IDA
IDA: 通过直接分析推断
34089617 MGI
enables integrin binding IDA
IDA: 通过直接分析推断
11323698 MGI
enables phosphatase binding IPI
IPI: 通过物理相互作用推断
9973385 MGI
enables protein phosphatase binding IPI
IPI: 通过物理相互作用推断
10026201 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within CD4-positive, alpha-beta T cell proliferation IMP
IMP: 通过突变表型推断
18792399 MGI
acts upstream of or within CD8-positive, alpha-beta T cell proliferation IMP
IMP: 通过突变表型推断
18792399 MGI
acts upstream of or within blood coagulation IMP
IMP: 通过突变表型推断
14557414 MGI
acts upstream of or within cellular response to lipopolysaccharide IMP
IMP: 通过突变表型推断
14557414 MGI
acts upstream of or within chemokine production IMP
IMP: 通过突变表型推断
15827966 MGI
acts upstream of or within cytokine production IMP
IMP: 通过突变表型推断
15827966 MGI
acts upstream of or within inflammatory response IMP
IMP: 通过突变表型推断
17761953 MGI
acts upstream of or within inflammatory response to antigenic stimulus IMP
IMP: 通过突变表型推断
19966208 MGI
involved in negative regulation of immunoglobulin production IMP
IMP: 通过突变表型推断
24935931 MGI
involved in negative regulation of mast cell activation IMP
IMP: 通过突变表型推断
12884301 MGI
involved in negative regulation of mast cell activation involved in immune response IDA
IDA: 通过直接分析推断
8855262 MGI
involved in negative regulation of mast cell activation involved in immune response IMP
IMP: 通过突变表型推断
11457897 MGI
involved in negative regulation of mast cell activation involved in immune response IPI
IPI: 通过物理相互作用推断
11323698 MGI
involved in negative regulation of monocyte activation IDA
IDA: 通过直接分析推断
34089617 MGI
involved in negative regulation of natural killer cell activation IDA
IDA: 通过直接分析推断
8977169 MGI
involved in negative regulation of plasma cell differentiation IMP
IMP: 通过突变表型推断
24935931 MGI
acts upstream of or within neutrophil homeostasis IMP
IMP: 通过突变表型推断
15827966 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: 通过突变表型推断
14557414 MGI
acts upstream of or within response to nematode IMP
IMP: 通过突变表型推断
17761953 MGI
acts upstream of or within response to other organism IMP
IMP: 通过突变表型推断
28883820 MGI
acts upstream of or within response to wounding IMP
IMP: 通过突变表型推断
14557414 MGI
acts upstream of or within type 2 immune response IMP
IMP: 通过突变表型推断
19966208 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
8855262 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
14557414 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

leukocyte immunoglobulin-like receptor subfamily B member 4A

leukocyte immunoglobulin-like receptor subfamily B member 4

glycoprotein 49 B

leukocyte immunoglobulin-like receptor, subfamily B, member 4

mast cell surface glycoprotein Gp49B

重组 Lilrb4a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72518 LILRB4/CD85k/ILT3 Protein, Mouse (HEK293, His) Q64281 (G24-K238) ≥95%
HY-P75866 LILRB4/CD85k/ILT3 Protein, Mouse (HEK293, Fc) Q64281 (M1-K238) ≥95%