1. Gene
  2. Hadh - hydroxyacyl-Coenzyme A dehydrogenase Gene

Hadh - hydroxyacyl-Coenzyme A dehydrogenase Gene

种属: Mus musculus

同用名: HCDH; Schad; Hadhsc

基因 ID: 15107 | 基因类型: protein coding

关于 Hadh

功能概要

Enables 3-hydroxyacyl-CoA dehydrogenase activity. Involved in positive regulation of cold-induced thermogenesis and regulation of Insulin secretion. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 4. Orthologous to human HADH (hydroxyacyl-CoA dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

Hadh 基因产物(1)

mRNA Protein Name
NM_008212.4 NP_032238.2 hydroxyacyl-coenzyme A dehydrogenase, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3-hydroxyacyl-CoA dehydrogenase activity IDA
IDA: 通过直接分析推断
15240869 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
20670938 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
21990309 MGI
involved in regulation of insulin secretion IMP
IMP: 通过突变表型推断
20670938 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
26767982 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain

hydroxylacyl-Coenzyme A dehydrogenase-dehydrogenase

medium and short chain L-3-hydroxyacyl-coenzyme A dehydrogenase

short-chain 3-hydroxyacyl-CoA dehydrogenase

重组 Hadh 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71563 HCDH Protein, Mouse (His-SUMO) Q61425 (S13-K314) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hadh NCBI NCBI:3033