CTSV - cathepsin V Gene

中文名称：组织蛋白酶 V

种属: Homo sapiens

同用名: CTSU; CATL2; CTSL2

关于 CTSV

功能概要

该基因编码的蛋白质是肽酶 C1 家族的一员，是一种溶酶体半胱氨酸蛋白酶，可能在角膜生理学中发挥重要作用。该基因在结直肠癌和乳腺癌中表达，但在正常结肠、乳腺或瘤周组织中不表达，表明该基因可能在肿瘤过程中发挥作用。已经鉴定出编码相同蛋白质的可变剪接变体。[RefSeq 提供，2011 年 1 月]

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011]