1. Gene
  2. Il23a - interleukin 23 subunit alpha Gene

Il23a - interleukin 23 subunit alpha Gene

中文名称:白细胞介素 23 亚基 α

种属: Rattus norvegicus

基因 ID: 155140 | 基因类型: protein coding

关于 Il23a

Primary_assembly 7: 721,809-723,923 reverse strand.mRatBN7.2:CM026980.1

This gene has 1 transcript (splice variant), 96 orthologues and is associated with 23 phenotypes. Biased expression in Thymus (RPKM 15.2), Spleen (RPKM 11.9) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动细胞因子活性。预计有助于白细胞介素 23 受体结合活性。预计参与多个过程,包括细胞因子产生的正调节;淋巴细胞活化的正调节;和肽酰酪氨酸磷酸化的正调节。预计在 T 细胞增殖的上游或内部起作用,并通过 RNA 聚合酶 II 对转录进行正调控。预计位于细胞外空间。预计是白细胞介素 23 复合物的一部分。与人 IL23A(白细胞介素 23 亚基 α)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable cytokine activity. Predicted to contribute to interleukin-23 receptor binding activity. Predicted to be involved in several processes, including positive regulation of cytokine production; positive regulation of lymphocyte activation; and positive regulation of peptidyl-tyrosine phosphorylation. Predicted to act upstream of or within T cell proliferation and positive regulation of transcription by RNA polymerase II. Predicted to be located in extracellular space. Predicted to be part of interleukin-23 complex. Orthologous to human IL23A (interleukin 23 subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Il23a 基因产物(1)

mRNA Protein Name
NM_130410.2 NP_569094.1 interleukin-23 subunit alpha precursor

Il23a 蛋白结构

IL23

IL23: pfam16649 (27 - 184)

  • 0
  • 100
  • 196 a.a.
蛋白主名 其他名称

interleukin-23 subunit alpha

IL-23 subunit alpha

IL-23-A

IL-23p19

Interleukin 23, alpha subunit p19

interleukin-23 subunit p19

重组 Il23a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73195 IL-23 alpha & IL-12 beta Heterodimer Protein, Rat (HEK293, His) NP_569094.1 (V22-A196) & EDM04146.1 (M23-S335) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il23a NCBI NCBI:51561
Mus musculus Il23a NCBI NCBI:83430