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  2. Il23a - interleukin 23, alpha subunit p19 Gene

Il23a - interleukin 23, alpha subunit p19 Gene

中文名称:白细胞介素 23 , α 亚基 p19

种属: Mus musculus

同用名: p19; IL-23

基因 ID: 83430 | 基因类型: protein coding

关于 Il23a

Chromosome 10: 128,132,008-128,134,621 reverse strand.GRCm39:CM001003.3

This gene has 2 transcripts (splice variants), 96 orthologues and is associated with 30 phenotypes. Low expression observed in reference dataset.

功能概要

有助于白细胞介素 23 受体结合活性。参与宿主对病毒防御反应的正向调控;免疫反应的正向调节;和中性粒细胞趋化性的正调节。在 T 细胞增殖和 RNA 聚合酶 II 的转录正调控的上游或内部起作用。位于细胞外空间。白细胞介素 23 复合物的一部分。在蜕膜中表达;基底蜕膜;胚胎;和胚外成分。与人 IL23A(白细胞介素 23 亚基 α)同源。 [由基因组资源联盟提供,2022 年 4 月]

Contributes to interleukin-23 receptor binding activity. Involved in positive regulation of defense response to virus by host; positive regulation of immune response; and positive regulation of neutrophil chemotaxis. Acts upstream of or within T cell proliferation and positive regulation of transcription by RNA polymerase II. Located in extracellular space. Part of interleukin-23 complex. Is expressed in decidua; decidua basalis; embryo; and extraembryonic component. Orthologous to human IL23A (interleukin 23 subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Il23a 基因产物(1)

mRNA Protein Name
NM_031252.2 NP_112542.1 interleukin-23 subunit alpha precursor

Il23a 蛋白结构

IL23

IL23: pfam16649 (27 - 184)

  • 0
  • 100
  • 196 a.a.
蛋白主名 其他名称

interleukin-23 subunit alpha

IL-23 subunit alpha

IL-23-A

IL-23p19

interleukin-23 subunit p19

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il23a NCBI NCBI:51561