1. Gene
  2. USP51 - ubiquitin specific peptidase 51 Gene

USP51 - ubiquitin specific peptidase 51 Gene

中文名称:泛素特异性肽酶 51

种属: Homo sapiens

基因 ID: 158880 | 基因类型: protein coding

关于 USP51

This gene has 2 transcripts (splice variants), 46 orthologues and 71 paralogues. Broad expression in thyroid (RPKM 4.9), ovary (RPKM 3.8) and 23 other tissues.

功能概要

启用染色质结合活性;组蛋白结合活性;和硫醇依赖性去泛素化酶。参与组蛋白去泛素化;调节细胞周期过程;和双链断裂修复的调节。预测位于染色体中。 [由基因组资源联盟提供,2022 年 4 月]

Enables chromatin binding activity; histone binding activity; and thiol-dependent Deubiquitinase. Involved in histone deubiquitination; regulation of cell cycle process; and regulation of double-strand break repair. Predicted to be located in chromosome. [provided by Alliance of Genome Resources, Apr 2022]

USP51 基因产物(1)

mRNA Protein Name
NM_201286.4 NP_958443.1 ubiquitin carboxyl-terminal hydrolase 51

USP51 蛋白结构

zf-UBP

zf-UBP: Zn-finger in ubiquitin-hydrolases and other protein (236 - 296)

UCH

UCH: Ubiquitin carboxyl-terminal hydrolase (363 - 703)

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  • 711 a.a.
蛋白主名 其他名称

ubiquitin carboxyl-terminal hydrolase 51

deubiquitinating enzyme 51

关联疾病

疾病名称 别名
Non-Syndromic X-Linked Intellectual Disability 99

Mrx99

X-Linked Mental Retardation 99

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus USP51 MGD MGI:3588217
Rattus norvegicus USP51 RGD RGD:1562211
Others USP51 NCBI