Ifnar1 - interferon (alpha and beta) receptor 1 Gene

中文名称：干扰素 (α 和 β) 受体 1

种属: Mus musculus

同用名: Ifar; Ifrc; Ifnar; Infar

关于 Ifnar1

功能概要

该基因编码的蛋白可启动 I 型干扰素结合活性和 I 型干扰素受体活性。参与细胞对细胞因子刺激的反应；大分子代谢过程的正向调控；和对脂多糖的反应。作用于多个过程的上游或内部，包括对病毒的防御反应；细胞因子产生的正调节；和调节肽基酪氨酸磷酸化。是质膜的组成部分。以多种结构表达，包括消化系统；中枢神经系统;泌尿生殖系统；外皮系统；和感觉器官。该基因的人类直系同源物与丙型肝炎有关。与人类 IFNAR1（干扰素 α 和 β 受体亚基 1）直系同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables type I interferon binding activity and type I interferon receptor activity. Involved in cellular response to cytokine stimulus; positive regulation of macromolecule metabolic process; and response to lipopolysaccharide. Acts upstream of or within several processes, including defense response to virus; positive regulation of cytokine production; and regulation of peptidyl-tyrosine phosphorylation. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in hepatitis C. Orthologous to human IFNAR1 (interferon alpha and beta receptor subunit 1). [provided by Alliance of Genome Resources, Apr 2022]