ALDH1L2 - aldehyde dehydrogenase 1 family member L2 Gene

中文名称：醛脱氢酶 1 家族成员 L2

种属: Homo sapiens

同用名: mtFDH

关于 ALDH1L2

功能概要

该基因编码醛脱氢酶超家族和甲酰基转移酶超家族的成员。该成员是 10-甲酰四氢叶酸脱氢酶 (FDH) 的线粒体形式，它在 NADP (+) 依赖性反应中将 10-甲酰四氢叶酸转化为四氢叶酸和 CO2，并且在细胞溶质之间的单碳基团分布中起重要作用和细胞的线粒体区室。已发现该基因的可变剪接转录本变体。[RefSeq 提供，2010 年 10 月]

This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010]