DECR1 - 2,4-dienoyl-CoA reductase 1 Gene

中文名称：2,4-二烯酰辅酶 A 还原酶 1

种属: Homo sapiens

同用名: DECR; NADPH; SDR18C1

基因 ID: 1666 | 基因类型: protein coding

关于 DECR1

Cytogenetic location: 8q21.3 Genomic coordinates (GRCh38): 8:90,001,477-90,053,633 (from NCBI)

This gene has 19 transcripts (splice variants), 212 orthologues and 1 paralogue. Ubiquitous expression in liver (RPKM 86.6), fat (RPKM 60.8) and 25 other tissues.

功能概要

该基因编码参与不饱和脂肪烯酰辅酶 A 酯的 β-氧化和代谢的辅助酶。[RefSeq 提供，2008 年 7 月]

This gene encodes an accessory Enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. [provided by RefSeq, Jul 2008]

DECR1 基因产物(2)

mRNA	Protein	Name
NM_001330575.2	NP_001317504.1	2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial isoform 2
NM_001359.2	NP_001350.1	2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial isoform 1 precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables 2,4-dienoyl-CoA reductase (NADPH) activity	IDA IDA: 通过直接分析推断	15531764	GOA
enables NADPH binding	IDA IDA: 通过直接分析推断	15531764	GOA
enables identical protein binding	IPI IPI: 通过物理相互作用推断	15531764	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in fatty acid beta-oxidation	IDA IDA: 通过直接分析推断	15531764	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
part of catalytic complex	IDA IDA: 通过直接分析推断	15531764	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DECR1 蛋白结构

adh_short_C2

0
100
200
300
335 a.a.

蛋白主名

其他名称

2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

2,4-dienoyl-CoA reductase 1, mitochondrial

关联疾病

疾病名称

别名

2,4-Dienoyl-Coa Reductase Deficiency

Progressive Encephalopathy With Leukodystrophy Due To Decr Deficiency	DECRD
2,4-Alpha Dienoyl-Coa Reductase Deficiency	Dienoyl-Coa Reductase Deficiency
Decr Deficiency With Hyperlysinemia

Hyperlysinemia, Type I

Hyperlysinemia	Lysine Intolerance
Alpha-Aminoadipic Semialdehyde Synthase Deficiency	Lysine:Alpha-Ketoglutarate Reductase Deficiency
L-Lysine:Nad-Oxido-Reductase Deficiency	Lysine Alpha-Ketoglutarate Reductase Deficiency
Alpha-Aminoadipic Semialdehyde Deficiency Disease	Lysine Alpha-Ketoglutarate Reductase Deficiency Disease
Saccharopinuria	Hyperlysinemia Type I
Hyperlysinemias	L-Lysine Nad-Oxido-Reductase Deficiency
Familial Hyperlysinemia	Saccharopine Dehydrogenase Deficiency Disease
Hyperlysinemia, 1	HYPLYS1
Saccharopine Dehydrogenase Deficiency

Hypogonadotropic Hypogonadism 2 With Or Without Anosmia

Kallmann Syndrome 2	Kal2
HH2	Hypogonadism, Hypogonadotropic, Type 2 With/Without Anosmia

Mitochondrial Complex I Deficiency, Nuclear Type 20

Acyl-Coa Dehydrogenase 9 Deficiency	Acad9 Deficiency
MC1DN20	Mitochondrial Complex I Deficiency Due To Acad9 Deficiency
Nuclear Type Mitochondrial Complex I Deficiency 20	Acyl-Coa Dehydrogenase Family, Member 9, Deficiency Of
Mitochondrial Complex 1 Deficiency Due To Acad9 Deficiency	Deficiency Of Acyl-Coa Dehydrogenase Family Member 9
Acyl-Coa Dehydrogenase Family, Member 9, Deficiency

Multiple Acyl-Coa Dehydrogenase Deficiency

MADD	Ethylmalonic-Adipicaciduria
Ema	Glutaric Acidemia Iia
Glutaric Acidemia Iib	Ga Ii
Glutaric Acidemia Iic	Glutaric Acidemia Type 2
Glutaric Acidemia Ii	Glutaric Aciduria Ii
Electron Transfer Flavoprotein Deficiency	Glutaric Aciduria Type 2
Mad Deficiency	Glutaric Acidemia Type Ii
Glutaric Aciduria 2	Etfa Deficiency
Etfb Deficiency	Etfdh Deficiency
Multiple Acyl Coenzyme A Dehydrogenase Deficiency	Ga2
Electron Transfer Flavoprotein Ubiquinone Oxidoreductase Deficiency	Electron Transfer Flavoprotein Dehydrogenase Deficiency
Ga 2	Glutaric Acidemia 2
Glutaric Acidemia, Type 2	Glutaric Aciduria, Type 2
Mad	Multiple Fad Dehydrogenase Deficiency
Ethylmalonic Adipic Aciduria	Glutaricaciduria Ii
Glutaric Aciduria 2a	GA2A
Gaiia	Glutaricaciduria Iia
Glutaric Aciduria 2b	GA2B
Gaiib	Glutaricaciduria Iib
Glutaric Aciduria 2c	GA2C
Gaiic	Glutaricaciduria Iic
Glutaricaciduria, Type Iia	Glutaric Acidemia Type 2a
Glutaric Acidemia Type 2c	Glutaric Aciduria Iia
Glutaric Aciduria Iib	Glutaric Aciduria Iic

Mitochondrial Complex I Deficiency, Nuclear Type 1

Mitochondrial Complex I Deficiency	Nadh:Q(1) Oxidoreductase Deficiency
MC1DN1	Nadh-Coenzyme Q Reductase Deficiency
Isolated Mitochondrial Respiratory Chain Complex I Deficiency	Isolated Nadh-Coenzyme Q Reductase Deficiency
Isolated Nadh-Coq Reductase Deficiency	Isolated Nadh-Ubiquinone Reductase Deficiency
Mitochondrial Nadh Dehydrogenase Component Of Complex I, Deficiency Of	Nuclear Type Mitochondrial Complex I Deficiency 1
Isolated Complex I Deficiency	Complex 1 Mitochondrial Respiratory Chain Deficiency
Nadh Coenzyme Q Reductase Deficiency	Complex I Mitochondrial Respiratory Chain Deficiency
Deficiency Of Mitochondrial Nadh Dehydrogenase Component Of Complex I	Nadh:Ubiquinone Oxidoreductase Deficiency
Complex I, Mitochondrial Respiratory Chain, Deficiency Of

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS03667	DECR1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	DECR1	RGD	RGD:70999
Bos taurus	DECR1	VGNC	VGNC:27982
Canis familiaris	DECR1	VGNC	VGNC:39871
Felis catus	DECR1	VGNC	VGNC:81646
Mus musculus	DECR1	MGD	MGI:1914710
Macaca mulatta	DECR1	VGNC	VGNC:81386

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站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

DECR1 - 2,4-dienoyl-CoA reductase 1 Gene

关于 DECR1

功能概要

DECR1 基因产物(2)

DECR1 蛋白结构

关联疾病

直系同源

热门区域

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DECR1 - 2,4-dienoyl-CoA reductase 1 Gene

关于 DECR1

功能概要

DECR1 基因产物(2)

DECR1 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z