1. Gene
  2. Lta4h - leukotriene A4 hydrolase Gene

Lta4h - leukotriene A4 hydrolase Gene

种属: Mus musculus

基因 ID: 16993 | 基因类型: protein coding

关于 Lta4h

功能概要

The protein encoded by this gene is an Enzyme that contains both hydrolase and Aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The Aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

Lta4h 基因产物(2)

mRNA Protein Name
NM_001313897.1 NP_001300826.1 leukotriene A-4 hydrolase isoform 2
NM_008517.2 NP_032543.2 leukotriene A-4 hydrolase isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23055941 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

leukotriene A-4 hydrolase

LTA-4 hydrolase

LTA4 hydrodase

tripeptide aminopeptidase LTA4H

重组 Lta4h 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74776 Leukotriene A4 Hydrolase/LTA4H Protein, Mouse (sf9, His) P24527 (M1-D611) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lta4h NCBI NCBI:4048