1. Gene
  2. Nbl1 - NBL1, DAN family BMP antagonist Gene

Nbl1 - NBL1, DAN family BMP antagonist Gene

种属: Mus musculus

同用名: DAN; NO3; Dana; D4H1S1733E

基因 ID: 17965 | 基因类型: protein coding

关于 Nbl1

功能概要

Enables BMP binding activity and morphogen activity. Involved in several processes, including determination of dorsal identity; negative regulation of monocyte chemotaxis; and sequestering of BMP in extracellular matrix. Acts upstream of or within negative regulation of BMP signaling pathway; neuron projection morphogenesis; and positive regulation of neuron differentiation. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain ventricular layer; embryo mesenchyme; limb; and nose. Orthologous to several human genes including MICOS10-NBL1 (MICOS10-NBL1 readthrough). [provided by Alliance of Genome Resources, Apr 2022]

Nbl1 基因产物(1)

mRNA Protein Name
NM_008675.2 NP_032701.2 neuroblastoma suppressor of tumorigenicity 1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables BMP binding IDA
IDA: 通过直接分析推断
9660951 MGI
enables morphogen activity IDA
IDA: 通过直接分析推断
9660951 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15528323 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in determination of dorsal identity IMP
IMP: 通过突变表型推断
9660951 MGI
acts upstream of or within negative regulation of BMP signaling pathway IDA
IDA: 通过直接分析推断
23676271 MGI
involved in negative regulation of monocyte chemotaxis IDA
IDA: 通过直接分析推断
15528323 MGI
involved in nervous system development IMP
IMP: 通过突变表型推断
9660951 MGI
acts upstream of neuron differentiation IDA
IDA: 通过直接分析推断
16325379 MGI
acts upstream of or within neuron projection morphogenesis IDA
IDA: 通过直接分析推断
16325379 MGI
acts upstream of or within positive regulation of neuron differentiation IDA
IDA: 通过直接分析推断
16325379 MGI
involved in sequestering of BMP in extracellular matrix IDA
IDA: 通过直接分析推断
9660951 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

neuroblastoma suppressor of tumorigenicity 1

N03

neuroblastoma, suppression of tumorigenicity 1

zinc finger protein DAN

重组 Nbl1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70076 DAND1 Protein, Mouse (HEK293, His) Q61477 (A17-D178) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nbl1 NCBI NCBI:4681