2. Gene
  3. Cd244a - CD244 molecule A Gene

Cd244a - CD244 molecule A Gene

  • 基因
  • 蛋白

种属: Mus musculus

同用名: 2B4; C9.1; Ly90; NAIL; Nmrk; Cd244; NKR2B4; SLAMF4; F730046O15Rik

基因 ID: 18106 | 基因类型: protein coding

关于 Cd244a

功能概要

Predicted to enable MHC class I protein binding activity. Involved in myeloid dendritic cell activation; natural killer cell activation involved in immune response; and positive regulation of lymphocyte proliferation. Located in external side of plasma membrane. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human CD244 (CD244 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd244a 基因产物(1)

mRNA Protein Name
NM_018729.2 NP_061199.2 natural killer cell receptor 2B4 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16127454 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in myeloid dendritic cell activation IMP
IMP: 通过突变表型推断
25643613 MGI
involved in natural killer cell activation involved in immune response IMP
IMP: 通过突变表型推断
15905190 MGI
involved in positive regulation of CD8-positive, alpha-beta T cell proliferation IMP
IMP: 通过突变表型推断
11739483 MGI
involved in positive regulation of natural killer cell proliferation IMP
IMP: 通过突变表型推断
15905190 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
10072077 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

natural killer cell receptor 2B4

CD244 natural killer cell receptor 2B4

NK cell receptor 2B4

NK cell type I receptor protein 2B4

SLAM family member 4

non-MHC restricted killing associated

signaling lymphocytic activation molecule 4

重组 Cd244a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72746 2B4/CD244 Protein, Mouse (HEK293, His) Q07763-1 (Q20-N221) ≥95%
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