2. Gene
  3. Ogdh - oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) Gene

Ogdh - oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: E1o; d1401; OGDH-E1; mKIAA4192; 2210403E04Rik; 2210412K19Rik

基因 ID: 18293 | 基因类型: protein coding

关于 Ogdh

功能概要

Enables oxoglutarate dehydrogenase (NAD+) activity. Acts upstream of or within brain development. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human OGDH (oxoglutarate dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

Ogdh 基因产物(9)

mRNA Protein Name
NM_001252282.1 NP_001239211.1 2-oxoglutarate dehydrogenase complex component E1 isoform 1
NM_001252283.1 NP_001239212.1 2-oxoglutarate dehydrogenase complex component E1 isoform 2
NM_001252287.2 NP_001239216.1 2-oxoglutarate dehydrogenase complex component E1 isoform 3 precursor
NM_001252288.1 NP_001239217.1 2-oxoglutarate dehydrogenase complex component E1 isoform 4
NM_001361902.1 NP_001348831.1 2-oxoglutarate dehydrogenase complex component E1 isoform 2
NM_001361903.1 NP_001348832.1 2-oxoglutarate dehydrogenase complex component E1 isoform 2
NM_001361904.1 NP_001348833.1 2-oxoglutarate dehydrogenase complex component E1 isoform 3 precursor
NM_001361905.1 NP_001348834.1 2-oxoglutarate dehydrogenase complex component E1 isoform 4
NM_010956.4 NP_035086.2 2-oxoglutarate dehydrogenase complex component E1 isoform 3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables oxoglutarate dehydrogenase (NAD+) activity IDA
IDA: 通过直接分析推断
17322295 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cerebellar cortex development IEP
IEP: 通过表达模式推断
16901643 MGI
involved in hippocampus development IEP
IEP: 通过表达模式推断
16901643 MGI
involved in olfactory bulb mitral cell layer development IEP
IEP: 通过表达模式推断
16901643 MGI
involved in pyramidal neuron development IEP
IEP: 通过表达模式推断
16901643 MGI
involved in striatum development IEP
IEP: 通过表达模式推断
16901643 MGI
involved in tangential migration from the subventricular zone to the olfactory bulb IEP
IEP: 通过表达模式推断
16901643 MGI
involved in thalamus development IEP
IEP: 通过表达模式推断
16901643 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
17322295 MGI
part of oxoglutarate dehydrogenase complex IMP
IMP: 通过突变表型推断
22169199 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

2-oxoglutarate dehydrogenase complex component E1

2-oxoglutarate dehydrogenase, mitochondrial

OGDC-E1

alpha-KGDH-E1

alpha-ketoglutarate dehydrogenase

oxoglutarate dehydrogenase (lipoamide)

thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase

重组 Ogdh 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71567 OGDC-E Protein, Mouse (His-SUMO) Q60597 (695V-1023S) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12688A Succinyl phosphonate trisodium salt Inhibitor ≥98.0% 否
HY-12688 Succinyl phosphonate Inhibitor / 否
HY-RS09758 OGDH Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ogdh NCBI NCBI:4967
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