1. Gene
  2. Pcolce - procollagen C-endopeptidase enhancer protein Gene

Pcolce - procollagen C-endopeptidase enhancer protein Gene

中文名称:前胶原C-内肽酶增强蛋白

种属: Mus musculus

同用名: P14; Astt2; Astt-2; PCPE-1

基因 ID: 18542 | 基因类型: protein coding

关于 Pcolce

Chromosome 5: 137,603,365-137,612,046 reverse strand.GRCm39:CM000998.3

This gene has 12 transcripts (splice variants), 246 orthologues, 35 paralogues and is associated with 9 phenotypes. Biased expression in adrenal adult (RPKM 519.4), ovary adult (RPKM 131.5) and 9 other tissues.

功能概要

预计该基因编码的蛋白可启动胶原蛋白结合活性;肝素结合活性;和肽酶激活剂活性。在对白血病抑制因子和蛋白水解的细胞反应的上游或内部起作用。位于细胞外空间。以多种结构表达,包括肾上腺;鳃弓;胚胎内胚层;下颌;和脐血管。与人 PCOLCE(前胶原 C-内肽酶增强剂)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable collagen binding activity; heparin binding activity; and peptidase activator activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor and proteolysis. Located in extracellular space. Is expressed in several structures, including adrenal gland; branchial arch; embryo endoderm; lower jaw; and umbilical blood vessel. Orthologous to human PCOLCE (procollagen C-endopeptidase enhancer). [provided by Alliance of Genome Resources, Apr 2022]

Pcolce 基因产物(1)

mRNA Protein Name
NM_008788.2 NP_032814.2 procollagen C-endopeptidase enhancer 1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
26220971 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
acts upstream of or within proteolysis IDA
IDA: 通过直接分析推断
7523404 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Pcolce 蛋白结构

CUB

CUB: cd00041 (35 - 145)

CUB

CUB: cd00041 (157 - 270)

NTR_PCOLCE

NTR_PCOLCE: cd03576 (333 - 459)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 468 a.a.
蛋白主名 其他名称

procollagen C-endopeptidase enhancer 1

astroglial cell transcript 2

procollagen C-proteinase enhancer 1

procollagen C-proteinase enhancer protein

procollagen COOH-terminal proteinase enhancer 1

type 1 procollagen C-proteinase enhancer protein

type I procollagen COOH-terminal proteinase enhancer

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pcolce NCBI NCBI:5118