Ptgir - prostaglandin I receptor (IP) Gene

中文名称：前列腺素 I 受体 ( IP)

种属: Mus musculus

同用名: IP; PGI2

关于 Ptgir

功能概要

预测该基因编码的蛋白编码的蛋白可启动前列环素受体活性。参与腺苷酸环化酶激活G蛋白偶联受体信号通路；血小板衍生生长因子受体信号通路的负调控；和平滑肌细胞增殖的负调节。作用于脂多糖的上游或响应之内。预测位于胞质溶胶中。预计在质膜上有活性。以多种结构表达，包括消化系统；胆囊;泌尿生殖系统；淋巴系统腺体；和肢体部分。与人类 PTGIR（前列腺素 I2 受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable prostacyclin receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of platelet-derived growth factor receptor signaling pathway; and negative regulation of smooth muscle cell proliferation. Acts upstream of or within response to lipopolysaccharide. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; gallbladder; genitourinary system; hemolymphoid system gland; and limb segment. Orthologous to human PTGIR (prostaglandin I2 receptor). [provided by Alliance of Genome Resources, Apr 2022]