1. Gene
  2. Reg1 - regenerating islet-derived 1 Gene

Reg1 - regenerating islet-derived 1 Gene

种属: Mus musculus

同用名: PSP; PTP

基因 ID: 19692 | 基因类型: protein coding

关于 Reg1

功能概要

Predicted to enable several functions, including growth factor activity; identical protein binding activity; and peptidoglycan binding activity. Involved in several processes, including pancreas regeneration; phosphatidylinositol 3-kinase signaling; and type B pancreatic cell differentiation. Acts upstream of or within with a positive effect on gene expression. Located in collagen-containing extracellular matrix. Is expressed in several structures, including esophagus; lung; and pancreas. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to several human genes including REG1A (regenerating family member 1 alpha). [provided by Alliance of Genome Resources, Apr 2022]

Reg1 基因产物(2)

mRNA Protein Name
NM_009042.2 NP_033068.1 lithostathine-1 precursor
NM_009042.2 NP_033068.1 lithostathine-1 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive effect gene expression IMP
IMP: 通过突变表型推断
16405968 MGI
involved in pancreas regeneration IMP
IMP: 通过突变表型推断
16405968 MGI
involved in phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
16405968 MGI
involved in positive regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
16405968 MGI
involved in type B pancreatic cell differentiation IMP
IMP: 通过突变表型推断
16405968 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

lithostathine-1

REG 1

islet of Langerhans regenerating protein 1

pancreatic stone protein 1

pancreatic thread protein 1

regenerating protein 1

重组 Reg1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71462 Lithostathine-1/Reg1 Protein, Mouse (His-SUMO) P43137 (22Q-165G) ≥95%

直系同源

种属 基因名 来源 基因 ID
Macaca fascicularis Reg1 NCBI
Rattus norvegicus Reg1 NCBI
Macaca mulatta Reg1 NCBI