Ren1 - renin 1 structural Gene

中文名称：肾素 1 结构

种属: Mus musculus

同用名: Ren; Rnr; Rn-1; Ren-1; Ren-A; Ren1c; Ren1d

关于 Ren1

功能概要

该基因编码的蛋白可启动内肽酶活性。在上游或内部对血压调节产生积极影响。在几个过程的上游或内部起作用，包括饮酒行为；男性性腺发育；肾素-血管紧张素对全身动脉血压的调节。位于细胞外空间。以多种结构表达，包括消化系统；脑;胚外成分；泌尿生殖系统；和行李箱。该基因的人类直系同源物与原发性高血压有关；家族性青少年高尿酸血症性肾病；手足口病；高血压;和门静脉高压症。与人类 REN（肾素）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables endopeptidase activity. Acts upstream of or within with a positive effect on regulation of blood pressure. Acts upstream of or within several processes, including drinking behavior; male gonad development; and regulation of systemic arterial blood pressure by renin-angiotensin. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and trunk. Human ortholog(s) of this gene implicated in essential hypertension; familial juvenile hyperuricemic nephropathy; hand, foot and mouth disease; hypertension; and portal hypertension. Orthologous to human REN (Renin). [provided by Alliance of Genome Resources, Apr 2022]