2. Gene
  3. Sema7a - sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A Gene

Sema7a - sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Semal; CDw108; sema L; sema K1; H-Sema-L; M-Sema-L; H-Sema K1; 2900057C09Rik

基因 ID: 20361 | 基因类型: protein coding

关于 Sema7a

功能概要

Enables Integrin binding activity. Involved in several processes, including integrin-mediated signaling pathway; positive regulation of ERK1 and ERK2 cascade; and positive regulation of macrophage cytokine production. Acts upstream of or within nervous system development and positive regulation of protein phosphorylation. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Orthologous to human SEMA7A (semaphorin 7A (John Milton Hagen blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Sema7a 基因产物(1)

mRNA Protein Name
NM_011352.3 NP_035482.1 semaphorin-7A precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables integrin binding IPI
IPI: 通过物理相互作用推断
17377534 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within axon extension IDA
IDA: 通过直接分析推断
12879062 MGI
acts upstream of or within axon extension IGI
IGI: 通过遗传相互作用推断
12879062 MGI
acts upstream of or within axon extension IMP
IMP: 通过突变表型推断
12879062 MGI
involved in integrin-mediated signaling pathway IDA
IDA: 通过直接分析推断
17377534 MGI
acts upstream of or within neuron projection development IMP
IMP: 通过突变表型推断
12879062 MGI
acts upstream of or within olfactory lobe development IDA
IDA: 通过直接分析推断
12879062 MGI
acts upstream of or within olfactory lobe development IMP
IMP: 通过突变表型推断
12879062 MGI
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
17377534 MGI
acts upstream of or within positive regulation of axon extension IDA
IDA: 通过直接分析推断
12879062 MGI
involved in positive regulation of macrophage cytokine production IDA
IDA: 通过直接分析推断
17377534 MGI
acts upstream of or within positive regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
12879062 MGI
acts upstream of protein phosphorylation IDA
IDA: 通过直接分析推断
12879062 MGI
involved in regulation of inflammatory response IDA
IDA: 通过直接分析推断
17377534 MGI
involved in regulation of synapse maturation IDA
IDA: 通过直接分析推断
25201975 MGI
involved in regulation of synapse maturation IMP
IMP: 通过突变表型推断
25201975 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
25201975 MGI
is active in GABA-ergic synapse IMP
IMP: 通过突变表型推断
25201975 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
17377534 MGI
is active in presynapse IDA
IDA: 通过直接分析推断
25201975 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

semaphorin-7A

semaphorin-K1

semaphorin-L

重组 Sema7a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78035 Semaphorin-7A/SEMA7A Protein, Mouse (HEK293, His) Q9QUR8 (Q45-A646) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12668 SEMA7A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sema7a NCBI NCBI:8482
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