1. Gene
  2. AMER3 - APC membrane recruitment protein 3 Gene

AMER3 - APC membrane recruitment protein 3 Gene

中文名称:APC 膜募集蛋白 3

种属: Homo sapiens

同用名: FAM123C

基因 ID: 205147 | 基因类型: protein coding

关于 AMER3

This gene has 4 transcripts (splice variants), 106 orthologues and 2 paralogues. Biased expression in brain (RPKM 2.4), stomach (RPKM 0.3) and 3 other tissues.

功能概要

预计具有 β-连环蛋白结合活性和磷脂酰肌醇-4,5-二磷酸结合活性。预计参与规范 Wnt 信号通路的调控。预测位于膜中。预计在质膜上有活性。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable beta-catenin binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in regulation of canonical Wnt signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

AMER3 基因产物(4)

mRNA Protein Name
NM_001105193.2 NP_001098663.1 APC membrane recruitment protein 3
NM_001105194.2 NP_001098664.1 APC membrane recruitment protein 3
NM_001105195.2 NP_001098665.1 APC membrane recruitment protein 3
NM_152698.3 NP_689911.2 APC membrane recruitment protein 3

AMER3 蛋白结构

WTX

WTX: WTX protein (88 - 173)

WTX

WTX: WTX protein (208 - 456)

  • 0
  • 200
  • 400
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  • 800
  • 861 a.a.
蛋白主名 其他名称

APC membrane recruitment protein 3

family with sequence similarity 123C

AMER3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
AMER3 Q8N944 AXIN2 Homo sapiens Q9Y2T1
Anti Tag CoIP
24251807
种属内
AMER3 Q8N944 AXIN2 Homo sapiens Q9Y2T1
Anti Bait CoIP
24251807
种属内
AMER3 Q8N944 AMER1 Homo sapiens Q5JTC6
Anti Bait CoIP
24251807
种属内
AMER3 Q8N944 APC Homo sapiens P25054
Anti Tag CoIP
24251807
种属内
AMER3 Q8N944 APC Homo sapiens P25054
Anti Bait CoIP
24251807
种属内
AMER3 Q8N944 APC Homo sapiens P25054
IF
24251807
种属内
AMER3 Q8N944 APC Homo sapiens P25054
Y2H
24251807
种属间
AMER3 Q8N944 Axin2 Mus musculus O88566
Anti Tag CoIP
24251807
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Tracheoesophageal Fistula With Or Without Esophageal Atresia

Esophageal Atresia With Or Without Tracheoesophageal Fistula

Esophageal Atresia

Esophageal Atresia

Tracheoesophageal Fistula

Congenital Atresia Of Esophagus

Congenital Imperforate Esophagus

Imperforate Esophagus

Oesophageal Atresia

Te Fistula

Tef

Tracheoesophageal Fistula With Or Without Esophageal Atresia

Esophageal Atresia/Tracheoesophageal Fistula

Esophageal Atresia And/Or Tracheoesophageal Fistula

Tracheoesophageal Fistula With Or Without Esohageal Atresia

Esophageal Atresia / Tracheoesophageal Fistula

Ea/Tef

Esophageal Atresia With Tracheoesophageal Fistula

Esophageal Atresia With Or Without Tracheoesophageal Fistula

Osteopathia Striata With Cranial Sclerosis

Hyperostosis Generalisata With Striations

Robinow-Unger Syndrome

OSCS

Osteopathia Striata Cranial Sclerosis

Osteopathia Striata-Cranial Sclerosis Syndrome

Horan-Beighton Syndrome

Os-Cs

Osteopathia Striata - Cranial Sclerosis

Voorhoeve Disease

Osc

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus AMER3 VGNC VGNC:25862
Rattus norvegicus AMER3 RGD RGD:1560420
Canis familiaris AMER3 VGNC VGNC:58289
Macaca mulatta AMER3 VGNC VGNC:69713
Mus musculus AMER3 MGD MGI:3026939