1. Gene
  2. Rnpep - arginyl aminopeptidase (aminopeptidase B) Gene

Rnpep - arginyl aminopeptidase (aminopeptidase B) Gene

中文名称:精氨酰氨肽酶 (氨肽酶 B)

种属: Mus musculus

基因 ID: 215615 | 基因类型: protein coding

关于 Rnpep

Chromosome 1: 135,190,450-135,211,822 reverse strand.GRCm39:CM000994.3

This gene has 9 transcripts (splice variants), 156 orthologues, 10 paralogues and is associated with 1 phenotype. Ubiquitous expression in duodenum adult (RPKM 45.6), large intestine adult (RPKM 34.3) and 28 other tissues.

功能概要

预测该基因编码的蛋白可启动金属氨基肽酶活性;肽结合活性;和过渡金属离子结合活性。预计参与血压和蛋白水解的负调节。预计位于多个细胞成分中,包括高尔基体;质膜的外侧;和分泌颗粒。预计在细胞外空间活跃。表达于中枢神经系统和感觉器官。与人 RNPEP(精氨酰氨肽酶)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable metalloaminopeptidase activity; peptide binding activity; and transition metal ion binding activity. Predicted to be involved in negative regulation of blood pressure and proteolysis. Predicted to be located in several cellular components, including Golgi apparatus; external side of plasma membrane; and secretory granule. Predicted to be active in extracellular space. Is expressed in central nervous system and sensory organ. Orthologous to human RNPEP (arginyl Aminopeptidase). [provided by Alliance of Genome Resources, Apr 2022]

Rnpep 基因产物(2)

mRNA Protein Name
NM_001159624.1 NP_001153096.1 aminopeptidase B isoform 2
NM_145417.3 NP_663392.2 aminopeptidase B isoform 1

Rnpep 蛋白结构

M1_LTA4H

M1_LTA4H: cd09599 (23 - 483)

Leuk-A4-hydro_C

Leuk-A4-hydro_C: pfam09127 (529 - 644)

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蛋白主名 其他名称

aminopeptidase B

AP-B

arginine aminopeptidase

cytosol aminopeptidase IV

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rnpep NCBI NCBI:6051