1. Gene
  2. RNPEP - arginyl aminopeptidase Gene

RNPEP - arginyl aminopeptidase Gene

中文名称:精氨酰氨肽酶

种属: Homo sapiens

同用名: APB; AP-B

基因 ID: 6051 | 基因类型: protein coding

关于 RNPEP

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:201,982,648-202,006,143 (from NCBI)

This gene has 14 transcripts (splice variants), 156 orthologues and 11 paralogues. Ubiquitous expression in duodenum (RPKM 31.1), colon (RPKM 27.9) and 25 other tissues.

功能概要

预测可启用金属氨基肽酶活性。预计参与蛋白水解。位于细胞外外泌体。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable metalloaminopeptidase activity. Predicted to be involved in proteolysis. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

RNPEP 基因产物(4)

mRNA Protein Name
NM_001319184.2 NP_001306113.1 aminopeptidase B isoform c
NM_001319183.2 NP_001306112.1 aminopeptidase B isoform c
NM_020216.4 NP_064601.3 aminopeptidase B isoform a
NM_001319182.2 NP_001306111.1 aminopeptidase B isoform b precursor

RNPEP 蛋白结构

Peptidase_M1

Peptidase_M1: Peptidase family M1 domain (36 - 417)

Leuk-A4-hydro_C

Leuk-A4-hydro_C: Leukotriene A4 hydrolase, C-terminal (500 - 644)

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  • 650 a.a.
蛋白主名 其他名称

aminopeptidase B

arginine aminopeptidase

关联疾病

疾病名称 别名
Histrionic Personality Disorder
Subacute Bacterial Endocarditis

Endocarditis Lenta

Sbe - Subacute Bacterial Endocarditis

Subacute Endocarditis, Lenta

Endocarditis, Subacute Bacterial

Haverhill Fever

Streptobacillosis

Streptobacillary Rat-Bite Fever

Streptobacillary Fever

Rat-Bite Fever Due To Streptobacillus Moniliformis

Erythema Arthriticum Epidemicum

Epidemic Arthritic Erythema

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus RNPEP VGNC VGNC:58406
Mus musculus RNPEP MGD MGI:2384902
Macaca mulatta RNPEP VGNC VGNC:76711
Rattus norvegicus RNPEP RGD RGD:621137
Canis familiaris RNPEP VGNC VGNC:45682
Felis catus RNPEP VGNC VGNC:64711