2. Gene
  3. Tnc - tenascin C Gene

Tnc - tenascin C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: TN; Hxb; Ten; TN-C; cytotactin; tenascin-C; C130033P17Rik

基因 ID: 21923 | 基因类型: protein coding

关于 Tnc

功能概要

Predicted to enable fibronectin binding activity and syndecan binding activity. Acts upstream of or within several processes, including neuromuscular junction development; peripheral nervous system axon regeneration; and prostate gland development. Located in collagen-containing extracellular matrix and extracellular region. Is expressed in several structures, including alimentary system; brain; immune system; ovary; and skeletal system. Human ortholog(s) of this gene implicated in allergic conjunctivitis; asthma; autosomal dominant nonsyndromic deafness 56; and pulmonary hypertension. Orthologous to human TNC (tenascin C). [provided by Alliance of Genome Resources, Apr 2022]

Tnc 基因产物(5)

mRNA Protein Name
NM_001369211.1 NP_001356140.1 tenascin isoform 1 precursor
NM_001369212.1 NP_001356141.1 tenascin isoform 3 precursor
NM_001369213.1 NP_001356142.1 tenascin isoform 4
NM_001369214.1 NP_001356143.1 tenascin isoform 5 precursor
NM_011607.3 NP_035737.2 tenascin isoform 2 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within mesenchymal-epithelial cell signaling involved in prostate gland development IMP
IMP: 通过突变表型推断
18950615 MGI
involved in morphogenesis of an epithelium IMP
IMP: 通过突变表型推断
18950615 MGI
acts upstream of or within neuromuscular junction development IMP
IMP: 通过突变表型推断
9593587 MGI
involved in neuromuscular junction development IMP
IMP: 通过突变表型推断
9593587 MGI
acts upstream of or within peripheral nervous system axon regeneration IMP
IMP: 通过突变表型推断
16262655 MGI
involved in peripheral nervous system axon regeneration IMP
IMP: 通过突变表型推断
16262655 MGI
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
19690384 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: 通过直接分析推断
19690384 MGI
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
19690384 MGI
acts upstream of or within prostate gland epithelium morphogenesis IMP
IMP: 通过突变表型推断
18950615 MGI
involved in regulation of inflammatory response IMP
IMP: 通过突变表型推断
10594729 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basement membrane IDA
IDA: 通过直接分析推断
7687262 MGI
located in collagen-containing extracellular matrix IDA
IDA: 通过直接分析推断
23658023 MGI
located in extracellular region IDA
IDA: 通过直接分析推断
8856503 MGI
located in interstitial matrix IDA
IDA: 通过直接分析推断
11767049 MGI
is active in perisynaptic extracellular matrix EXP
EXP: 通过实验结果推断
16452087 MGI
is active in perisynaptic extracellular matrix IDA
IDA: 通过直接分析推断
16452087 MGI
part of tenascin complex IPI
IPI: 通过物理相互作用推断
14709716 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tenascin

hexabrachion

重组 Tnc 蛋白

目录号 产品名 蛋白编号 纯度
HY-P700002 Tenascin/Tnc protein, Mouse (His-Myc) Q80YX1 (G1884-N2099) ≥95%
HY-P700834 Tenascin/Tnc protein, Mouse (HEK293, His) Q80YX1-1 (G23-S621) ≥95%
HY-P700002A Tenascin/Tnc protein, Mouse (His-Myc, Solution) Q80YX1 (G1884-N2099) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14783 TNC Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnc NCBI NCBI:3371
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