2. Gene
  3. Cd40lg - CD40 ligand Gene

Cd40lg - CD40 ligand Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: IGM; IMD3; Ly62; TRAP; gp39; CD154; Cd40l; HIGM1; Ly-62; T-BAM; CD40-L; Tnfsf5; Tnlg8b

基因 ID: 21947 | 基因类型: protein coding

关于 Cd40lg

功能概要

Predicted to enable CD40 receptor binding activity and Integrin binding activity. Involved in isotype switching. Acts upstream of or within B cell differentiation and regulation of immunoglobulin production. Located in external side of plasma membrane. Is expressed in Meckel's cartilage; dorsal root ganglion; and limb. Used to study inflammatory bowel disease and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; artery disease (multiple); autoimmune disease (multiple); combined T cell and B cell immunodeficiency (multiple); and hematologic Cancer (multiple). Orthologous to human CD40LG (CD40 ligand). [provided by Alliance of Genome Resources, Apr 2022]

Cd40lg 基因产物(1)

mRNA Protein Name
NM_011616.3 NP_035746.2 CD40 ligand
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within B cell differentiation IGI
IGI: 通过遗传相互作用推断
14647274 MGI
acts upstream of or within immunoglobulin production IGI
IGI: 通过遗传相互作用推断
15485634 MGI
involved in isotype switching IDA
IDA: 通过直接分析推断
7529792 MGI
acts upstream of or within regulation of immunoglobulin production IDA
IDA: 通过直接分析推断
12958312 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
17082577 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CD40 ligand

T-cell antigen Gp39

TNF-related activation protein

tumor necrosis factor ligand 8b

tumor necrosis factor ligand superfamily member 5

重组 Cd40lg 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70808 CD40L/CD154/TRAP Protein, Mouse (HEK293, His) P27548 (M112-L260) ≥95%
HY-P72908 CD40L/CD154/TRAP Protein, Mouse (HEK293, Fc) P27548 (G115-L260) ≥95%
HY-P78271 CD40L/CD154/TRAP Trimer Protein, Mouse (HEK293, Fc) P27548 (M112-L260) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99845 Dazodalibep 99.90% Phase 3
Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02247 CD40LG Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd40lg NCBI NCBI:959
Leporidae Cd40lg NCBI
Macaca mulatta Cd40lg NCBI NCBI:574160
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z