ZSCAN25 - zinc finger and SCAN domain containing 25 Gene

中文名称：含锌指和 SCAN 域 25

种属: Homo sapiens

同用名: ZNF498

基因 ID: 221785 | 基因类型: protein coding

关于 ZSCAN25

This gene has 10 transcripts (splice variants), 88 orthologues and 31 paralogues. Ubiquitous expression in small intestine (RPKM 5.1), duodenum (RPKM 3.7) and 25 other tissues.

功能概要

该基因编码的蛋白质与锌指蛋白有一些相似之处，锌指蛋白参与 DNA 结合和蛋白质-蛋白质相互作用。已经确定了多个选择性剪接的转录本变体，但其中大多数的全长性质尚未确定。[RefSeq 提供，2008 年 7 月]

This gene encodes a protein that bears some similarity to zinc finger proteins, which are involved in DNA binding and protein-protein interactions. Multiple alternatively spliced transcript variants have been identified, but the full-length nature for most of them has not been determined. [provided by RefSeq, Jul 2008]

ZSCAN25 基因产物(9)

mRNA	Protein	Name
NM_001350979.2	NP_001337908.1	zinc finger and SCAN domain-containing protein 25 isoform a
NM_001350980.2	NP_001337909.1	zinc finger and SCAN domain-containing protein 25 isoform a
NM_001350981.2	NP_001337910.1	zinc finger and SCAN domain-containing protein 25 isoform b
NM_001350982.2	NP_001337911.1	zinc finger and SCAN domain-containing protein 25 isoform b
NM_001350983.2	NP_001337912.1	zinc finger and SCAN domain-containing protein 25 isoform b
NM_001350984.2	NP_001337913.1	zinc finger and SCAN domain-containing protein 25 isoform c
NM_001350985.2	NP_001337914.1	zinc finger and SCAN domain-containing protein 25 isoform c
NM_001350986.2	NP_001337915.1	zinc finger and SCAN domain-containing protein 25 isoform d
NM_145115.3	NP_660090.2	zinc finger and SCAN domain-containing protein 25 isoform a

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZSCAN25 蛋白结构

SCAN

zf-C2H2

zf-H2C2_2

0
100
200
300
400
500
544 a.a.

蛋白主名

其他名称

zinc finger and SCAN domain-containing protein 25

zinc finger protein 498

关联疾病

疾病名称

别名

Hypertension, Essential

Essential Hypertension	Hypertension
High Blood Pressure	Hypertension, Essential, Susceptibility To
Hypertensive Disease	Primary Hypertension
EHT	Hypertension, Salt-Sensitive Essential, Susceptibility To
Hyperpiesia	Idiopathic Hypertension
Hypertensive Disorder	Hypertension, Essential, Susceptibility To, 3
Hypertension, Essential 3	Hypertension, Essential, Salt-Sensitive
Hypertension, Essential, Susceptibility To, 6	Hypertension, Essential 6
Hypertension, Salt-Sensitive Essential	Hypertension, Susceptibility To
Hypertension, Essential, Susceptibility To, 4	Hypertension, Essential 4
Hypertension, Essential, Susceptibility To, 2	Hypertension, Essential 2
Hypertension, Essential, Susceptibility To, 1	Hypertension, Essential 1
Hypertension, Essential, Susceptibility To, 5	Hypertension, Essential 5
Htn	Vascular Hypertensive Disorder
Systemic Primary Arterial Hypertension	Hbp - [High Blood Pressure]
Systemic Arterial Hypertensive Disorder	Elevated Blood Pressure
Arterial Hypertension Nos	Hypertension Nos
Benign Hypertension	Systemic Arterial Hypertension
Systemic Hypertension	Artery Htn
Benign Htn	Vascular Htn
Vascular Hypertension	Cholesterol Hypertension
Cholesterol Htn	Idiopathic Htn
Malignant Hypertension	Malignant Htn
Raised Blood Pressure	Cardiovascular Hypertension
Primary Htn - [Hypertension]	High Arterial Tension
High Blood Pressure Disorder	Ht - [Hypertension]
Htn - [Hypertension]	Hypertensive Vascular Disease
Hypertensive Vascular Degeneration

Avoidant Personality Disorder

Anxious Personality Disorder

Personality Disorders

Pituitary Adenoma 1, Multiple Types

Pituitary Adenoma Predisposition	PITA1
Isolated Familial Somatotropinoma	Fis
Ifs	Somatotrophinoma, Familial
Acromegaly Due To Pituitary Adenoma 1	Pagh1
Pituitary Adenoma 1	Somatotropinoma, Familial Isolated
Somatotropic Adenoma	Somatotropinoma
Pituitary Gigantism	Hypophyseal Gigantism
Infantile And Juvenile Forms Of Acromegaly	Acromegaly Due To Pituitary Adenoma
Familial Isolated Pituitary Adenoma	Familial Isolated Somatotropinomas
Familial Somatotrophinoma	Fipa
Pituitary Adenoma, Growth Hormone-Secreting, 1	Gigantism Pituitary
Pituitary Adenoma, Type 1, Multiple Types	Gigantism
Pituitary Adenoma, Familial Isolated	Multiple Gastrointestinal Atresias

Expressive Language Disorder

Developmental Expressive Language Disorder

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS16201	ZSCAN25 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	ZSCAN25	MGD	MGI:3647079
Canis familiaris	ZSCAN25	VGNC	VGNC:48852
Macaca mulatta	ZSCAN25	VGNC	VGNC:79344
Rattus norvegicus	ZSCAN25	RGD	RGD:1308619

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