1. Gene
  2. Vtn - vitronectin Gene

Vtn - vitronectin Gene

种属: Mus musculus

同用名: Vn

基因 ID: 22370 | 基因类型: protein coding

关于 Vtn

功能概要

Enables extracellular matrix binding activity. Involved in oligodendrocyte differentiation. Acts upstream of or within cell-matrix adhesion; extracellular matrix organization; and positive regulation of cell-substrate adhesion. Located in extracellular matrix. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; metanephros; and retina. Human ortholog(s) of this gene implicated in Churg-Strauss syndrome; granulomatosis with polyangiitis; and thrombosis. Orthologous to human VTN (vitronectin). [provided by Alliance of Genome Resources, Apr 2022]

Vtn 基因产物(1)

mRNA Protein Name
NM_011707.2 NP_035837.1 vitronectin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables extracellular matrix binding IDA
IDA: 通过直接分析推断
18757743 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell-matrix adhesion IDA
IDA: 通过直接分析推断
15728191 MGI
acts upstream of or within extracellular matrix organization IDA
IDA: 通过直接分析推断
18757743 MGI
involved in oligodendrocyte differentiation IDA
IDA: 通过直接分析推断
23155445 MGI
acts upstream of or within positive regulation of cell-substrate adhesion IDA
IDA: 通过直接分析推断
18757743 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular matrix IDA
IDA: 通过直接分析推断
15728191 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

vitronectin

S-protein

serum-spreading factor

重组 Vtn 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73484 Vitronectin Protein, Mouse (HEK293, His) P29788 (D20-K478) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vtn NCBI NCBI:7448