CD93 - CD93 molecule Gene

中文名称：CD93 分子

种属: Homo sapiens

同用名: C1QR1; C1qRP; CDw93; ECSM3; MXRA4; C1qR(P); dJ737E23.1

关于 CD93

功能概要

该基因编码的蛋白质是一种细胞表面糖蛋白和 I 型膜蛋白，最初被确定为骨髓细胞特异性标记物。编码的蛋白质曾被认为是 C1q 的受体，但现在被认为是参与细胞间粘附和凋亡细胞的清除。已发现该蛋白质的细胞内细胞质尾与 moesin 相互作用，moesin 是一种已知在将跨膜蛋白连接到细胞骨架和细胞骨架重塑中起作用的蛋白质。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the Cytoskeleton and in the remodelling of the Cytoskeleton. [provided by RefSeq, Jul 2008]