2. Gene
  3. FAIM2 - Fas apoptotic inhibitory molecule 2 Gene

FAIM2 - Fas apoptotic inhibitory molecule 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：Fas 凋亡抑制分子 2

种属: Homo sapiens

同用名: LFG; LFG2; NGP35; NMP35; TMBIM2

基因 ID: 23017 | 基因类型: protein coding

关于 FAIM2

Cytogenetic location: 12q13.12 Genomic coordinates (GRCh38): 12:49,866,896-49,903,900 (from NCBI)

This gene has 7 transcripts (splice variants), 259 orthologues and 5 paralogues. Biased expression in brain (RPKM 125.6) and adrenal (RPKM 12.3).

功能概要

参与调节神经元凋亡过程。通过死亡域受体作用于外在凋亡信号通路的负调节上游或负调节内。位于膜筏内。 [由基因组资源联盟提供，2022 年 4 月]

Involved in regulation of neuron apoptotic process. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway via death domain receptors. Located in membrane raft. [provided by Alliance of Genome Resources, Apr 2022]

FAIM2 基因产物(1)

mRNA Protein Name
NM_012306.4 NP_036438.2 protein lifeguard 2

FAIM2 蛋白结构

Bax1-I

Bax1-I: Inhibitor of apoptosis-promoting Bax1 (101 - 311)

  • 0
  • 100
  • 200
  • 316 a.a.
蛋白主名 其他名称

protein lifeguard 2

neural membrane protein 35

FAIM2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
FAIM2 Q9BWQ8 EPN2 Homo sapiens O95208-2
Y2H Array
32296183
种属内
FAIM2 Q9BWQ8 EPN2 Homo sapiens O95208-2
Y2H Prey Pooling
32296183
种属内
FAIM2 Q9BWQ8 GGT6 Homo sapiens Q6P531
Y2H Prey Pooling
32296183
种属内
FAIM2 Q9BWQ8 GGT6 Homo sapiens Q6P531
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04675 FAIM2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus FAIM2 VGNC VGNC:62043
Mus musculus FAIM2 MGD MGI:1919643
Canis familiaris FAIM2 VGNC VGNC:40571
Bos taurus FAIM2 VGNC VGNC:28710
Macaca mulatta FAIM2 VGNC VGNC:72286
Rattus norvegicus FAIM2 RGD RGD:628744
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z