2. Gene
  3. CUL9 - cullin 9 Gene

CUL9 - cullin 9 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：卡林 9

种属: Homo sapiens

同用名: PARC; H7AP1

基因 ID: 23113 | 基因类型: protein coding

关于 CUL9

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:43,182,196-43,224,587 (from NCBI)

This gene has 18 transcripts (splice variants), 243 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 6.1), skin (RPKM 5.9) and 25 other tissues.

功能概要

预计将启用多种功能，包括 ATP 绑定活动；金属离子结合活性；和泛素蛋白连接酶结合活性。参与微管细胞骨架组织；蛋白质泛素化；和有丝分裂核分裂的调节。位于胞质溶胶中。 cullin-RING 泛素连接酶复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable several functions, including ATP binding activity; metal ion binding activity; and ubiquitin protein Ligase binding activity. Involved in microtubule Cytoskeleton organization; protein ubiquitination; and regulation of mitotic nuclear division. Located in cytosol. Part of cullin-RING ubiquitin Ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

CUL9 基因产物(1)

mRNA Protein Name
NM_015089.4 NP_055904.1 cullin-9

CUL9 蛋白结构

Cul7

Cul7: Mouse development and cellular proliferation protein Cullin-7 (366 - 440)

ANAPC10

ANAPC10: Anaphase-promoting complex, subunit 10 (APC10) (1182 - 1300)

Cullin

Cullin: Cullin family (1415 - 1836)

IBR

IBR: IBR domain, a half RING-finger domain (2141 - 2203)

IBR

IBR: IBR domain, a half RING-finger domain (2231 - 2273)

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  • 2517 a.a.
蛋白主名 其他名称

cullin-9

CUL-9

CUL9 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CUL9 Q8IWT3 TP53 Homo sapiens P04637
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Amelogenesis Imperfecta, Hypomaturation Type, Iia3

Amelogenesis Imperfecta Hypomaturation Type 2a3

AI2A3

Amelogenesis Imperfecta Hypomaturation Type Iia3

Amelogenesis Imperfecta, Type Iia3

Amelogenesis Imperfecta Type Iia3

Amelogenesis Imperfecta, Hypomaturation Type, 2a3
Three M Syndrome 1

3-M Syndrome

Yakut Short Stature Syndrome

3m Syndrome

Le Merrer Syndrome

Dolichospondylic Dysplasia

Gloomy Face Syndrome

Three M Syndrome

3M1

3m Syndrome 1

Miller-Mckusick-Malvaux Syndrome

3-Msbn

Three-M Slender-Boned Nanism

Miller-Mckusick-Malvaux-Syndrome

3-M Syndrome 1

3m Syndrome-1

3m Syndrome, Type 1

Dwarfism

Dwarfism Tall Vertebrae
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03366 CUL9 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris CUL9 VGNC VGNC:39735
Mus musculus CUL9 MGD MGI:1925559
Bos taurus CUL9 VGNC VGNC:27836
Felis catus CUL9 VGNC VGNC:61288
Macaca mulatta CUL9 VGNC VGNC:71416
Rattus norvegicus CUL9 RGD RGD:1562008
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