2. Gene
  3. ICE1 - interactor of little elongation complex ELL subunit 1 Gene

ICE1 - interactor of little elongation complex ELL subunit 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：小伸长复合体 ELL 亚基 1 的相互作用体

种属: Homo sapiens

同用名: KIAA0947

基因 ID: 23379 | 基因类型: protein coding

关于 ICE1

Cytogenetic location: 5p15.32 Genomic coordinates (GRCh38): 5:5,422,677-5,490,220 (from NCBI)

This gene has 3 transcripts (splice variants), 209 orthologues and 2 paralogues. Ubiquitous expression in ovary (RPKM 7.5), brain (RPKM 7.4) and 25 other tissues.

功能概要

启用蛋白质-大分子适配器活动。参与多个过程，包括细胞内蛋白质转运的正调节； RNA 聚合酶 III 对转录的正调控；和 snRNA 转录。位于 Cajal 体内；组蛋白基因座体；和转录活性染色质。转录延伸因子复合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein-macromolecule adaptor activity. Involved in several processes, including positive regulation of intracellular protein transport; positive regulation of transcription by RNA polymerase III; and snRNA transcription. Located in Cajal body; histone locus body; and transcriptionally active chromatin. Part of transcription elongation factor complex. [provided by Alliance of Genome Resources, Apr 2022]

ICE1 基因产物(1)

mRNA Protein Name
NM_015325.3 NP_056140.1 little elongation complex subunit 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22195968 GOA
enables protein-macromolecule adaptor activity IDA
IDA: 通过直接分析推断
23932780 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of intracellular protein transport IMP
IMP: 通过突变表型推断
23932780 GOA
involved in positive regulation of protein-containing complex assembly IMP
IMP: 通过突变表型推断
23932780 GOA
involved in positive regulation of transcription by RNA polymerase III IMP
IMP: 通过突变表型推断
23932780 GOA
involved in snRNA transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
22195968 GOA
involved in snRNA transcription by RNA polymerase III IMP
IMP: 通过突变表型推断
23932780 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Cajal body IDA
IDA: 通过直接分析推断
22195968 GOA
located in euchromatin IDA
IDA: 通过直接分析推断
22195968 GOA
located in histone locus body IDA
IDA: 通过直接分析推断
23932780 GOA
part of transcription elongation factor complex IDA
IDA: 通过直接分析推断
23932780 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

little elongation complex subunit 1

interactor of little elongator complex ELL subunit 1

关联疾病

疾病名称 别名
Cri-Du-Chat Syndrome

5p Deletion Syndrome

5p Partial Monosomy Syndrome

Monosomy 5p

Cat Cry Syndrome

Chromosome 5p Deletion Syndrome

Cri Du Chat Syndrome

5p- Syndrome

5p Minus Syndrome

Chromosome 5p- Syndrome

Chromosome 5 Short Arm Deletion Syndrome

Chromosome 5p Deletion

Deletion 5p

Cri Du Chat

5p Partial Deletion Syndrome

Partial Deletion Of Short Arm Of Chromosome 5 Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06517 ICE1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ICE1 RGD RGD:1309747
Canis familiaris ICE1 VGNC VGNC:41858
Mus musculus ICE1 MGD MGI:2385865
Bos taurus ICE1 VGNC VGNC:30026
Macaca mulatta ICE1 VGNC VGNC:73457
Felis catus ICE1 VGNC VGNC:62867
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