2. Gene
  3. Tnfsf13b - tumor necrosis factor (ligand) superfamily, member 13b Gene

Tnfsf13b - tumor necrosis factor (ligand) superfamily, member 13b Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: BAFF; BLyS; TALL1; THANK; zTNF4; TALL-1; Tnlg7a; TNFSF20; D8Ertd387e

基因 ID: 24099 | 基因类型: protein coding

关于 Tnfsf13b

功能概要

Predicted to enable receptor ligand activity. Involved in B cell differentiation and tumor necrosis factor-mediated signaling pathway. Acts upstream of or within B cell homeostasis; positive regulation of germinal center formation; and positive regulation of lymphocyte activation. Predicted to be located in several cellular components, including focal adhesion; perinuclear region of cytoplasm; and plasma membrane. Predicted to be active in extracellular space. Is expressed in genitourinary system. Used to study IgA glomerulonephritis and Sjogren's syndrome. Orthologous to human TNFSF13B (TNF Superfamily member 13b). [provided by Alliance of Genome Resources, Apr 2022]

Tnfsf13b 基因产物(2)

mRNA Protein Name
NM_001347309.1 NP_001334238.1 tumor necrosis factor ligand superfamily member 13B isoform 2
NM_033622.2 NP_296371.1 tumor necrosis factor ligand superfamily member 13B isoform 1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within B cell costimulation IDA
IDA: 通过直接分析推断
15240667 MGI
acts upstream of or within B cell differentiation IMP
IMP: 通过突变表型推断
17581616 MGI
involved in B cell differentiation IMP
IMP: 通过突变表型推断
18624351 MGI
acts upstream of or within B cell homeostasis IMP
IMP: 通过突变表型推断
14557413 MGI
acts upstream of B cell proliferation IDA
IDA: 通过直接分析推断
15240667 MGI
acts upstream of or within T cell costimulation IDA
IDA: 通过直接分析推断
15240667 MGI
acts upstream of T cell proliferation IDA
IDA: 通过直接分析推断
15240667 MGI
acts upstream of or within cytokine production IDA
IDA: 通过直接分析推断
17581616 MGI
acts upstream of or within cytokine production IMP
IMP: 通过突变表型推断
17581616 MGI
acts upstream of germinal center formation IMP
IMP: 通过突变表型推断
14557413 MGI
acts upstream of or within immunoglobulin production IGI
IGI: 通过遗传相互作用推断
15485634 MGI
acts upstream of or within immunoglobulin production IMP
IMP: 通过突变表型推断
17581616 MGI
acts upstream of or within positive regulation of B cell proliferation IDA
IDA: 通过直接分析推断
15240667 MGI
acts upstream of or within positive regulation of T cell proliferation IDA
IDA: 通过直接分析推断
15240667 MGI
acts upstream of or within positive regulation of germinal center formation IMP
IMP: 通过突变表型推断
14557413 MGI
acts upstream of or within regulation of immune response IMP
IMP: 通过突变表型推断
14557413 MGI
acts upstream of or within skin development IMP
IMP: 通过突变表型推断
17581616 MGI
acts upstream of or within transitional one stage B cell differentiation IMP
IMP: 通过突变表型推断
17581616 MGI
involved in tumor necrosis factor-mediated signaling pathway IGI
IGI: 通过遗传相互作用推断
18624351 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tumor necrosis factor ligand superfamily member 13B

b cell-activating factor

tumor necrosis factor ligand 7a

重组 Tnfsf13b 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70816 BAFF/TNFSF13B Protein, Mouse (HEK293, Fc) Q9WU72-1 (A127-L309) ≥95%
HY-P700161AF Animal-Free BAFF/TNFSF13B Protein, Mouse (His) Q9WU72 (A127-L309) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14824 TNFSF13B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnfsf13b NCBI NCBI:10673
Canis familiaris Tnfsf13b NCBI NCBI:485545
Macaca fascicularis Tnfsf13b NCBI NCBI:102123214
Macaca mulatta Tnfsf13b NCBI NCBI:693917
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