Agtr2 - angiotensin II receptor, type 2 Gene

中文名称：血管紧张素 II 受体，2 型

种属: Rattus norvegicus

同用名: AT2R; AT2-R; AT2R

关于 Agtr2

功能概要

预测该基因编码的蛋白编码的蛋白可启动血管紧张素 II 型受体活性。参与多个过程，包括醛固酮分泌；动物器官发育；和分泌调节。位于细胞质和质膜的核周区。用于研究慢性肾病；先天性膈疝;肾小球肾炎（多发性）；高血压（多发性）；和胎粪吸入综合征。多种疾病的生物标志物，包括哮喘；充血性心力衰竭;肾小球硬化症（多发性）；高血压;和 2 型糖尿病。与 IgA 肾小球肾炎有关的该基因的人类直系同源物；晚期肾脏疾病;低血糖;智力残疾;和膀胱输尿管反流。与人类 AGTR2（血管紧张素 II 受体 2 型）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable angiotensin type II receptor activity. Involved in several processes, including aldosterone secretion; animal organ development; and regulation of secretion. Located in perinuclear region of cytoplasm and plasma membrane. Used to study chronic kidney disease; congenital diaphragmatic hernia; glomerulonephritis (multiple); hypertension (multiple); and meconium aspiration syndrome. Biomarker of several diseases, including asthma; congestive heart failure; glomerulosclerosis (multiple); hypertension; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; end stage renal disease; hypoglycemia; intellectual disability; and vesicoureteral reflux. Orthologous to human AGTR2 (angiotensin II receptor type 2). [provided by Alliance of Genome Resources, Apr 2022]