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  3. Acvr1c - activin A receptor type 1C Gene

Acvr1c - activin A receptor type 1C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：1 C 型激活素 A 受体

种属: Rattus norvegicus

同用名: Alk7; Alk-7; habrec1

基因 ID: 245921 | 基因类型: protein coding

关于 Acvr1c

Primary_assembly 3: 42,822,610-42,892,327 reverse strand.mRatBN7.2:CM026976.1

This gene has 4 transcripts (splice variants), 215 orthologues, 11 paralogues and is associated with 1 phenotype. Biased expression in Thymus (RPKM 72.2), Brain (RPKM 64.9) and 7 other tissues.

功能概要

该基因编码的蛋白可启动多项功能，包括 ATP 绑定活动； BMP受体结合活性；和激活素结合活性。参与多个过程，包括大脑发育；对葡萄糖的反应；和转化生长因子β受体复合物组装。位于细胞表面；细胞质；和质膜。激活素受体复合物的一部分。与人类 ACVR1C（1C 型激活素 A 受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables several functions, including ATP binding activity; BMP Receptor binding activity; and activin binding activity. Involved in several processes, including brain development; response to glucose; and transforming growth factor beta receptor complex assembly. Located in cell surface; cytoplasm; and plasma membrane. Part of activin receptor complex. Orthologous to human ACVR1C (Activin A receptor type 1C). [provided by Alliance of Genome Resources, Apr 2022]

Acvr1c 基因产物(1)

mRNA Protein Name
NM_139090.2 NP_620790.2 activin receptor type-1C precursor

Acvr1c 蛋白结构

Activin_recp

Activin_recp: pfam01064 (25 - 94)

TGF_beta_GS

TGF_beta_GS: pfam08515 (165 - 192)

STKc_TGFbR1_ACVR1b_ACVR1c

STKc_TGFbR1_ACVR1b_ACVR1c: cd14143 (198 - 485)

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  • 493 a.a.
蛋白主名 其他名称

activin receptor type-1C

ACTR-IC

TGF-beta type 1 receptor

activin A receptor, type IC

activin receptor type IC

activin receptor-like kinase 7

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00242 ACVR1C Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS00243 Acvr1c Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS00244 Acvr1c Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Acvr1c NCBI NCBI:130399
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