Slc5a2 - solute carrier family 5 (sodium/glucose cotransporter), member 2 Gene

中文名称：溶质载体家族 5 (钠/葡萄糖协同转运蛋白) ，成员 2

种属: Mus musculus

同用名: Sglt2

关于 Slc5a2

功能概要

预测该基因编码的蛋白可启动 D-葡萄糖跨膜转运蛋白活性； α-葡萄糖苷跨膜转运蛋白活性；和葡萄糖：钠同向转运体活性。预计参与多个过程，包括α-葡萄糖苷转运；跨质膜导入；和肾钾排泄。预测作用于碳水化合物转运和离子转运的上游或内部。预测位于刷状缘膜。预计在质膜上有活性。预计是膜的组成部分。在泌尿系统中表达。该基因的人类直系同源物与肾糖尿有关。与人类 SLC5A2（溶质载体家族 5 成员 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable D-glucose transmembrane transporter activity; alpha-glucoside transmembrane transporter activity; and glucose:sodium symporter activity. Predicted to be involved in several processes, including alpha-glucoside transport; import across plasma membrane; and renal potassium excretion. Predicted to act upstream of or within carbohydrate transport and ion transport. Predicted to be located in brush border membrane. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Is expressed in urinary system. Human ortholog(s) of this gene implicated in renal glycosuria. Orthologous to human SLC5A2 (solute carrier family 5 member 2). [provided by Alliance of Genome Resources, Apr 2022]