Slc2a1 - solute carrier family 2 member 1 Gene

中文名称：溶质载体家族 2 成员 1

种属: Rattus norvegicus

同用名: GTG1; Gtg3; GLUTB; Glut1; RATGTG1

关于 Slc2a1

功能概要

该基因编码的蛋白可启动多种功能，包括 D-葡萄糖跨膜转运蛋白活性；脱氢抗坏血酸跨膜转运蛋白活性；和激酶结合活性。参与多个过程，包括细胞高渗反应；细胞对机械刺激的反应；和脱氢抗坏血酸运输。位于多个细胞成分中，包括 Z 盘；基底外侧质膜；和插盘。与肌膜共定位。高血压的生物标志物；甲状腺功能减退症;和大脑中动脉梗塞。该基因的人类直系同源物与脑部疾病有关（多个）；碳水化合物代谢紊乱；脊髓脊膜膨出；肥胖;和 2 型糖尿病。与人类 SLC2A1（溶质载体家族 2 成员 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables several functions, including D-glucose transmembrane transporter activity; dehydroascorbic acid transmembrane transporter activity; and kinase binding activity. Involved in several processes, including cellular hyperosmotic response; cellular response to mechanical stimulus; and dehydroascorbic acid transport. Located in several cellular components, including Z disc; basolateral plasma membrane; and intercalated disc. Colocalizes with sarcolemma. Biomarker of hypertension; hypothyroidism; and middle cerebral artery infarction. Human ortholog(s) of this gene implicated in brain disease (multiple); carbohydrate metabolic disorder; myelomeningocele; obesity; and type 2 diabetes mellitus. Orthologous to human SLC2A1 (solute carrier family 2 member 1). [provided by Alliance of Genome Resources, Apr 2022]