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  3. ALPG - alkaline phosphatase, germ cell Gene

ALPG - alkaline phosphatase, germ cell Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：碱性磷酸酶，生殖细胞

种属: Homo sapiens

同用名: GCAP; ALPPL; ALPPL2

基因 ID: 251 | 基因类型: protein coding

关于 ALPG

Cytogenetic location: 2q37.1 Genomic coordinates (GRCh38): 2:232,406,844-232,410,714 (from NCBI)

This gene has 1 transcript (splice variant), 361 orthologues and 3 paralogues. Biased expression in placenta (RPKM 6.1), lung (RPKM 0.8) and 1 other tissue.

功能概要

至少有四种不同但相关的碱性磷酸酶：肠、胎盘、胎盘样和肝/骨/肾 (组织非特异性) 。该基因的产物是一种膜结合糖基化酶，定位于睾丸、胸腺和某些生殖细胞肿瘤，与胎盘和肠道形式的碱性磷酸酶密切相关。[RefSeq 提供，2008 年 7 月]

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated Enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of Alkaline Phosphatase. [provided by RefSeq, Jul 2008]

ALPG 基因产物(1)

mRNA Protein Name
NM_031313.3 NP_112603.2 alkaline phosphatase, germ cell type preproprotein
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alkaline phosphatase activity IDA
IDA: 通过直接分析推断
1939159 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ALPG 蛋白结构

Alk_phosphatase

Alk_phosphatase: Alkaline phosphatase (52 - 487)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 532 a.a.
蛋白主名 其他名称

alkaline phosphatase, germ cell type

ALP-1

重组 ALPG 蛋白

目录号 产品名 蛋白编号 纯度
HY-P700951 Alkaline Phosphatase/ALPG Protein, Human (Biotinylated, HEK293, His-Avi) P10696 (I20-D503) ≥95%
HY-P700952 Alkaline Phosphatase/ALPG Protein, Human (HEK293, His) P10696 (I20-D503) ≥95%

关联疾病

疾病名称 别名
Seminoma

Seminoma, Pure
Gonadoblastoma

GBY
Germ Cell Cancer

Malignant Germ Cell Tumor

Neoplasms, Germ Cell And Embryonal

Germ Cell Neoplasm

Germ Cell Tumour

Malignant Tumor Of The Germ Cell

Neoplasms Germ Cell

Malignant Germ Cell Neoplasm
Mixed Type Thymoma

Thymoma, Mixed Type

Thymoma, Type Ab
Endodermal Sinus Tumor

Yolk Sac Tumor

Endodermal Sinus Tumour

Hepatoid Yolk Sac Tumour

Infantile Embryonal Carcinoma

Yolk Sac Neoplasm

Yolk Sac Tumour
Dysgerminoma
Embryonal Carcinoma

Embryonal Neoplasm

Embryonal Cancer

Primary Extragonadal Embryonal Carcinoma

Embryo Neoplasm

Carcinoma Embryonal

Cancer Embryonal

Carcinoma, Embryonal

Extragonadal Embryonal Carcinoma

Cancer, Embryonal
Choriocarcinoma

Chorioepithelioma
Complete Androgen Insensitivity Syndrome

Cais

Complete Androgen Resistance Syndrome

Androgen Insensitivity Syndrome Complete

Androgen Insensitivity, Complete

Androgen-Insensitivity Syndrome

Testicular Feminization
Androgen Insensitivity Syndrome

Androgen Resistance Syndrome

AIS

Testicular Feminization Syndrome

Androgen Receptor Deficiency

Dhtr Deficiency

Dihydrotestosterone Receptor Deficiency

Ar Deficiency

Testicular Feminization

Tfm

Androgen Insensitivity

Androgen-Insensitivity Syndrome

Goldberg-Maxwell Syndrome

Complete Androgen Insensitivity Syndrome

Cais

Feminisation - Testicular

Goldberg - Maxwell Syndrome

Androgen Insensitivity Syndrome, Complete

Morris Syndrome

Ary

AR

Insensitivity Syndrome, Androgen

Androgen Insensitivity Nos
Testis Seminoma

Seminoma Of Testis

Seminoma Testis

Testicular Seminoma Pure

Seminoma
Hypophosphatasia

Phosphoethanolaminuria

Childhood Hypophosphatasia

Deficiency Of Alkaline Phosphatase

Hypophospatasia, Childhood

Hypophosphatasia Mild

Phosphoethanol-Aminuria

Rathburn Disease

Hpp

Rathbun Disease

Hypophosphatasia, Childhood

Infantile Hypophosphatasia
Cryptorchidism, Unilateral Or Bilateral

Cryptorchidism

Undescended Testicle

Undescended Testis

Cryptorchism

Undescended Testicles

CRYPTO

Impaired Testicular Descent

Cryptosporidiosis

Retained Testis

Unilateral Cryptorchidism

Unilateral Undescended Testis

Nondescent Unilateral Testicle

Unilateral Cryptorchism

Ectopic Testis, Unilateral

Bilateral Cryptorchidism

Bilateral Cryptorchism

Bilateral Nondescent Testicle

Bilateral Undescended Testes

Bilateral Ectopic Testes
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00627 ALPG Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ALPG RGD RGD:1565100
Mus musculus ALPG NCBI
Others ALPG NCBI
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