Fgfr4 - fibroblast growth factor receptor 4 Gene

中文名称：成纤维细胞生长因子受体 4

种属: Rattus norvegicus

关于 Fgfr4

功能概要

预测该基因编码的蛋白编码的蛋白可启动成纤维细胞生长因子结合活性；成纤维细胞生长因子激活受体活性；和肝素结合活性。作用于成纤维细胞生长因子受体信号通路的上游或内部。预计位于多个细胞成分中，包括高尔基体；内质网；和运输囊泡。预计是受体复合体的一部分。预计是质膜的组成部分。预测与细胞-细胞连接共定位。该基因的人类直系同源物与癌症有关（多个）；肝硬化;前列腺癌;和胃癌。与人 FGFR4（成纤维细胞生长因子受体 4）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable Fibroblast Growth Factor binding activity; fibroblast growth factor-activated receptor activity; and heparin binding activity. Acts upstream of or within Fibroblast Growth Factor receptor signaling pathway. Predicted to be located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and transport vesicle. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Predicted to colocalize with cell-cell junction. Human ortholog(s) of this gene implicated in carcinoma (multiple); liver cirrhosis; prostate cancer; and stomach Cancer. Orthologous to human FGFR4 (Fibroblast Growth Factor receptor 4). [provided by Alliance of Genome Resources, Apr 2022]