Casp1 - caspase 1 Gene

中文名称：半胱天冬酶 1

种属: Rattus norvegicus

同用名: Ice; p45; Il1bc

关于 Casp1

功能概要

该基因编码的蛋白可启动支架蛋白结合活性。参与多个过程，包括成肌细胞融合；昼夜节律睡眠/觉醒周期的正向调节，非快速眼动睡眠；和 IL-1 β 产生的正向调节。位于细胞质中；神经元投射；和核。部分含蛋白质复合物。用于研究急性肾功能衰竭和视觉性癫痫。与人类 CASP1（caspase 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables scaffold protein binding activity. Involved in several processes, including myoblast fusion; positive regulation of circadian sleep/wake cycle, non-REM sleep; and positive regulation of interleukin-1 beta production. Located in cytoplasm; neuron projection; and nucleus. Part of protein-containing complex. Used to study acute kidney failure and visual epilepsy. Orthologous to human CASP1 (Caspase 1). [provided by Alliance of Genome Resources, Apr 2022]