2. Gene
  3. FUT5 - fucosyltransferase 5 Gene

FUT5 - fucosyltransferase 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品

中文名称：岩藻糖基转移酶 5

种属: Homo sapiens

同用名: FUC-TV

基因 ID: 2527 | 基因类型: protein coding

关于 FUT5

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:5,865,826-5,870,540 (from NCBI)

This gene has 2 transcripts (splice variants), 382 orthologues and 7 paralogues. Biased expression in colon (RPKM 6.2), esophagus (RPKM 5.3) and 8 other tissues.

功能概要

启用 3-半乳糖基-N-乙酰氨基葡萄糖 4-α-L-岩藻糖基转移酶活性和 4-半乳糖基-N-乙酰氨基葡萄糖 3-α-L-岩藻糖基转移酶活性。参与神经酰胺代谢过程和寡糖代谢过程。预测位于高尔基体膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity and 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity. Involved in ceramide metabolic process and oligosaccharide metabolic process. Predicted to be located in Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022]

FUT5 基因产物(1)

mRNA Protein Name
NM_002034.2 NP_002025.2 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity IDA
IDA: 通过直接分析推断
1740457 GOA
enables 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity IDA
IDA: 通过直接分析推断
1740457 GOA
enables fucosyltransferase activity IDA
IDA: 通过直接分析推断
7721776 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ceramide metabolic process IDA
IDA: 通过直接分析推断
7721776 GOA
involved in oligosaccharide metabolic process IDA
IDA: 通过直接分析推断
1740457 GOA
involved in protein N-linked glycosylation IDA
IDA: 通过直接分析推断
29593094 GOA
involved in protein O-linked glycosylation IDA
IDA: 通过直接分析推断
29593094 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FUT5 蛋白结构

Glyco_transf_10

Glyco_transf_10: Glycosyltransferase family 10 (fucosyltransferase) C-term (56 - 373)

  • 0
  • 100
  • 200
  • 300
  • 374 a.a.
蛋白主名 其他名称

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5

3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5

关联疾病

疾病名称 别名
Drug-Induced Lupus Erythematosus

Dile

Dil

Drug-Induced Systemic Lupus Erythematosus
Dowling-Degos Disease

Reticular Pigment Anomaly Of Flexures

Dark Dot Disease

Reticulate Acropigmentation Of Kitamura

Dowling-Degos Kitamura Disease

Kitamura Reticulate Acropigmentation

Ddd

Dowling-Degos-Kitamura Disease

Reticular Pigmented Anomaly Of Flexures
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05156 FUT5 Human Pre-designed siRNA Set A Pre-designed Sets / 否
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