1. Gene
  2. Fth1 - ferritin heavy chain 1 Gene

Fth1 - ferritin heavy chain 1 Gene

种属: Rattus norvegicus

同用名: Fth

基因 ID: 25319 | 基因类型: protein coding

关于 Fth1

功能概要

Predicted to enable ferric iron binding activity and ferrous iron binding activity. Involved in negative regulation of fibroblast proliferation and negative regulation of necrotic cell death. Predicted to be located in autolysosome. Predicted to be active in cytoplasm. Biomarker of congestive heart failure and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in hemochromatosis type 5. Orthologous to human FTH1 (ferritin heavy chain 1). [provided by Alliance of Genome Resources, Apr 2022]

Fth1 基因产物(1)

mRNA Protein Name
NM_012848.2 NP_036980.1 ferritin heavy chain
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19244528 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of fibroblast proliferation IDA
IDA: 通过直接分析推断
9924025 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ferritin heavy chain

Ferritin subunit H

ferritin H subunit

ferritin, heavy polypeptide 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fth1 NCBI NCBI:2495