2. Gene
  3. Mmp7 - matrix metallopeptidase 7 Gene

Mmp7 - matrix metallopeptidase 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：基质金属肽酶 7

种属: Rattus norvegicus

同用名: MPMM

基因 ID: 25335 | 基因类型: protein coding

关于 Mmp7

Primary_assembly 8: 4,848,186-4,855,902 forward strand.mRatBN7.2:CM026981.1

This gene has 3 transcripts (splice variants), 163 orthologues, 23 paralogues and is associated with 35 phenotypes. Restricted expression toward (RPKM 175.4).

功能概要

该基因编码的蛋白可启动肝素结合活性。涉及多个过程，包括细胞对机械刺激的反应；动情周期；和女性怀孕所涉及的母体过程。位于细胞表面和细胞外空间。用于研究高血压和前列腺癌。膀胱颈梗阻的生物标志物；冠状动脉再狭窄；高血压;前列腺癌;和肾性高血压。与人 MMP7（基质金属肽酶 7）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables heparin binding activity. Involved in several processes, including cellular response to mechanical stimulus; estrous cycle; and maternal process involved in female pregnancy. Located in cell surface and extracellular space. Used to study hypertension and prostate carcinoma. Biomarker of bladder neck obstruction; coronary restenosis; hypertension; prostate cancer; and renal hypertension. Orthologous to human MMP7 (matrix metallopeptidase 7). [provided by Alliance of Genome Resources, Apr 2022]

Mmp7 基因产物(1)

mRNA Protein Name
NM_012864.2 NP_036996.1 matrilysin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables heparin binding IDA
IDA: 通过直接分析推断
10660581 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to mechanical stimulus IEP
IEP: 通过表达模式推断
20054150 RGD
involved in estrous cycle IEP
IEP: 通过表达模式推断
10070364 RGD
involved in maternal process involved in female pregnancy IEP
IEP: 通过表达模式推断
10645258 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
17670906 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
10660581 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
23256367 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Mmp7 蛋白结构

PG_binding_1

PG_binding_1: pfam01471 (33 - 84)

Peptidase_M10

Peptidase_M10: pfam00413 (105 - 261)

  • 0
  • 100
  • 200
  • 267 a.a.
蛋白主名 其他名称

matrilysin

MMP-7

Matrix metalloproteinase 7 (matrilysin)

matrin

matrix metalloproteinase-7

pump-1 protease

uterine metalloproteinase

重组 Mmp7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P700574 MMP-7 Protein, Rat (P. pastoris, His) P50280 (F98-L267) ≥95%

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-12169 Marimastat Inhibitor ≥98.0% Phase 3
Pre-clinical Phase
生物活性分子 (14)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13564 Batimastat Inhibitor 98.92% 否
HY-103444 ARP-100 Inhibitor ≥99.0% 否
HY-N0774 Isofraxidin Inhibitor 99.00% 否
HY-151540 MMP-7-IN-1 Inhibitor 99.68% 否
HY-131498 MOCAc-PLGL(Dpa)AR 99.86% 否
HY-156430 MMP-7-IN-3 Inhibitor 99.93% 否
HY-RS08552 Mmp7 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-153563 MMP-7-IN-2 Inhibitor 99.34% 否
HY-119423 MMP Inhibitor II Inhibitor ≥99.0% 否
HY-161169 TP0628103 Inhibitor / 否
HY-130076 MMP-2 Inhibitor II Inhibitor / 否
HY-RS08551 MMP7 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS08553 Mmp7 Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-13564A Batimastat sodium salt Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mmp7 NCBI NCBI:4316
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