2. Gene
  3. CADM2 - cell adhesion molecule 2 Gene

CADM2 - cell adhesion molecule 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：细胞粘附分子 2

种属: Homo sapiens

同用名: NECL3; IGSF4D; Necl-3; synCAM2; SynCAM 2

基因 ID: 253559 | 基因类型: protein coding

关于 CADM2

Cytogenetic location: 3p12.1 Genomic coordinates (GRCh38): 3:84,958,989-86,074,429 (from NCBI)

This gene has 5 transcripts (splice variants), 273 orthologues and 14 paralogues. Biased expression in brain (RPKM 29.4), fat (RPKM 2.4) and 1 other tissue.

功能概要

该基因编码属于免疫球蛋白 (Ig) 超家族的突触细胞粘附分子 1 (SynCAM) 家族的成员。编码的蛋白质具有三个 Ig 样结构域和一个靠近 C 末端的胞质蛋白 4.1 结合位点。属于蛋白质 4.1 家族的蛋白质交联血影蛋白并与其他细胞骨架蛋白相互作用。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2012 年 2 月]

This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with Other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

CADM2 基因产物(14)

mRNA Protein Name
NM_001167674.2 NP_001161146.1 cell adhesion molecule 2 isoform 1 precursor
NM_001167675.2 NP_001161147.1 cell adhesion molecule 2 isoform 2 precursor
NM_001256502.2 NP_001243431.1 cell adhesion molecule 2 isoform 4
NM_001256503.2 NP_001243432.1 cell adhesion molecule 2 isoform 4
NM_001256504.2 NP_001243433.1 cell adhesion molecule 2 isoform 5
NM_001256505.2 NP_001243434.1 cell adhesion molecule 2 isoform 5
NM_001375960.1 NP_001362889.1 cell adhesion molecule 2 isoform 6 precursor
NM_001375961.1 NP_001362890.1 cell adhesion molecule 2 isoform 7
NM_001375964.1 NP_001362893.1 cell adhesion molecule 2 isoform 8 precursor
NM_001375967.1 NP_001362896.1 cell adhesion molecule 2 isoform 9 precursor
NM_001375968.1 NP_001362897.1 cell adhesion molecule 2 isoform 10 precursor
NM_001381963.1 NP_001368892.1 cell adhesion molecule 2 isoform 11 precursor
NM_001381964.1 NP_001368893.1 cell adhesion molecule 2 isoform 1 precursor
NM_153184.4 NP_694854.2 cell adhesion molecule 2 isoform 3 precursor

CADM2 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (27 - 109)

C2-set_2

C2-set_2: CD80-like C2-set immunoglobulin domain (140 - 210)

I-set

I-set: Immunoglobulin I-set domain (229 - 313)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 435 a.a.
蛋白主名 其他名称

cell adhesion molecule 2

immunoglobulin superfamily member 4D

重组 CADM2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75599 CADM2/IGSF4D Protein, Human (HEK293, His) Q8N3J6-2 (G30-D335) ≥95%

关联疾病

疾病名称 别名
Cannabis Dependence

Marijuana Abuse

Cannabinoid Addiction

Cannabinoid Dependence

Cannabis Addiction
Hallucinogen Dependence

Hallucinogen Addiction
Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

ADHD

Attention Deficit Disorder

Attention Deficit-Hyperactivity Disorder, Susceptibility To

Attention Deficit Disorder With Hyperactivity

Hyperkinetic Disorder

Hyperactivity Of Childhood

Attention-Deficit/Hyperactivity Disorder

Add

Addh

Attention Deficit

Attention Deficit Disorder Of Childhood With Hyperactivity

Attention Deficit Disorder With Hyperactivity Syndrome

Hyperkinetic Syndrome

Attention-Deficit Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

Disturbance Of Activity And Attention

Disorder Of Activity And Attention

Adhd - [Attention Deficit Hyperactivity Disorder]

Hyperkinetic Disorders

Disorder Of Activity And Attention With Hyperkinesia

Attention Deficit Syndrome With Hyperactivity
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01820 CADM2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta CADM2 VGNC VGNC:70674
Mus musculus CADM2 MGD MGI:2442722
Felis catus CADM2 VGNC VGNC:102609
Rattus norvegicus CADM2 RGD RGD:1305678
Canis familiaris CADM2 VGNC VGNC:38656
Bos taurus CADM2 VGNC VGNC:26695
Others CADM2 NCBI
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