2. Gene
  3. Ifng - interferon gamma Gene

Ifng - interferon gamma Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: If2f; IFNG2

基因 ID: 25712 | 基因类型: protein coding

关于 Ifng

功能概要

Predicted to enable cytokine activity. Involved in several processes, including negative regulation of cell population proliferation; positive regulation of NMDA glutamate receptor activity; and positive regulation of macromolecule metabolic process. Located in several cellular components, including extracellular space; neuron projection; and perikaryon. Used to study several diseases, including Chagas disease; allergic conjunctivitis; allergic rhinitis; renal fibrosis; and ureteral obstruction. Biomarker of several diseases, including abdominal aortic aneurysm; autoimmune thyroiditis; pulpitis; tongue squamous cell carcinoma; and visual epilepsy. Human ortholog(s) of this gene implicated in several diseases, including ataxia telangiectasia; autoimmune disease (multiple); eczema herpeticum; Factor VIII deficiency; and leukemia (multiple). Orthologous to human IFNG (interferon gamma). [provided by Alliance of Genome Resources, Apr 2022]

Ifng 基因产物(1)

mRNA Protein Name
NM_138880.3 NP_620235.1 interferon gamma precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cytokine activity IDA
IDA: 通过直接分析推断
20624457 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in microglial cell activation IGI
IGI: 通过遗传相互作用推断
27094552 RGD
involved in negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
11940252 RGD
involved in negative regulation of epithelial cell differentiation IDA
IDA: 通过直接分析推断
20624457 RGD
involved in negative regulation of fibroblast proliferation IDA
IDA: 通过直接分析推断
1906384 RGD
involved in negative regulation of glomerular mesangial cell proliferation IMP
IMP: 通过突变表型推断
1906384 RGD
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
20624457 RGD
involved in neuroinflammatory response IDA
IDA: 通过直接分析推断
27235345 RGD
involved in positive regulation of MHC class II biosynthetic process IEP
IEP: 通过表达模式推断
3127329 RGD
involved in positive regulation of NMDA glutamate receptor activity IGI
IGI: 通过遗传相互作用推断
27094552 RGD
involved in positive regulation of apoptotic process IDA
IDA: 通过直接分析推断
12931271 RGD
involved in positive regulation of cell adhesion IDA
IDA: 通过直接分析推断
2509328 RGD
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
20624457 RGD
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
27235345 RGD
involved in positive regulation of neuron differentiation IDA
IDA: 通过直接分析推断
19355840 RGD
involved in positive regulation of receptor signaling pathway via STAT IDA
IDA: 通过直接分析推断
20624457 RGD
involved in positive regulation of synaptic transmission, cholinergic IDA
IDA: 通过直接分析推断
1900518 RGD
involved in regulation of glial cell proliferation IDA
IDA: 通过直接分析推断
10598324 RGD
involved in regulation of hepatocyte proliferation IDA
IDA: 通过直接分析推断
15799032 RGD
involved in regulation of neuronal action potential IDA
IDA: 通过直接分析推断
7715823 RGD
involved in regulation of the force of heart contraction IDA
IDA: 通过直接分析推断
1900518 RGD
involved in response to tacrolimus IEP
IEP: 通过表达模式推断
23867624 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
19439114 RGD
involved in sensory perception of mechanical stimulus IDA
IDA: 通过直接分析推断
7715823 RGD
involved in type II interferon-mediated signaling pathway IDA
IDA: 通过直接分析推断
20624457 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
2474612 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
9396771 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interferon gamma

IFN-gamma

interferon 2f

重组 Ifng 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7095 IFN-gamma Protein, Rat P01581 (G24-C156) ≥95%
HY-P7095A IFN-gamma Protein, Rat (CHO) P01581 (Q23-C156) ≥95%
HY-P73254 IFN-gamma Protein, Rat (HEK293, Fc) P01581 (Q23-C156) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99292 Fontolizumab Inhibitor 97.18% Phase 2
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-149916 A2AR-antagonist-1 Antagonist / 否
HY-P10497 EBV BZLF1 (190-197) Inhibitor / 否
HY-RS06587 IFNG Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-117786 Go 7874 Inhibitor / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990324 Anti-AA2AR/Adenosine A2aR Antibody (3F6-9G5) Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ifng NCBI NCBI:3458
Canis familiaris Ifng NCBI NCBI:403801
Macaca fascicularis Ifng NCBI NCBI:102128291
Mus musculus Ifng NCBI NCBI:15978
Susscrofa domestica Ifng NCBI
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