TIAM2 - TIAM Rac1 associated GEF 2 Gene

中文名称：TIAM Rac1 相关 GEF 2

种属: Homo sapiens

同用名: STEF; TIAM-2

关于 TIAM2

功能概要

该基因编码鸟嘌呤核苷酸交换因子。一种高度相似的小鼠蛋白特异性激活 Ras 相关的 C3 肉毒杆菌底物 1，将这种 Rho 样鸟苷三磷酸酶 (GTPase) 从鸟苷二磷酸结合的非活性状态转变为鸟苷三磷酸结合的活性状态。编码的蛋白质可能在神经细胞发育中发挥作用。已经描述了编码不同亚型的选择性剪接转录物变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]