OPN1MW - opsin 1, medium wave sensitive Gene

中文名称：视蛋白 1，中波敏感

种属: Homo sapiens

同用名: CBD; GCP; GOP; CBBM; COD5; OPN1MW1

基因 ID: 2652 | 基因类型: protein coding

关于 OPN1MW

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:154,182,596-154,196,861 (from NCBI)

This gene has 3 transcripts (splice variants), 235 orthologues, 9 paralogues and is associated with 7 phenotypes. Low expression observed in reference dataset.

功能概要

该基因编码视蛋白基因家族的一种吸光视觉色素。编码的蛋白质称为绿锥感光色素或中波长敏感视蛋白。视蛋白是具有七个跨膜结构域、一个 N 端胞外结构域和一个 C 端胞质结构域的 G 蛋白偶联受体。长波长视蛋白基因和中波长视蛋白基因的多个拷贝串联排列在 X 染色体上，这些序列之间可能发生频繁的不等重组和基因转换。 X 染色体可能具有中长波视蛋白基因的融合，或者可能具有这些基因的多个拷贝。该基因的缺陷是深绿色色盲的原因。[RefSeq 提供，2009 年 3 月]

This gene encodes for a LIGHT absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009]

OPN1MW 基因产物(1)

mRNA	Protein	Name
NM_000513.2	NP_000504.1	medium-wave-sensitive opsin 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables identical protein binding	IDA IDA: 通过直接分析推断	28402104	GOA
enables photoreceptor activity	IMP IMP: 通过突变表型推断	8185948	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in positive regulation of cytokinesis	IMP IMP: 通过突变表型推断	22888021	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in plasma membrane	IDA IDA: 通过直接分析推断	20579627	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

OPN1MW 蛋白结构

7tm_1

0
100
200
300
364 a.a.

蛋白主名

其他名称

medium-wave-sensitive opsin 1

Medium-wave-sensitive opsin 2

关联疾病

疾病名称

别名

Colorblindness, Partial, Deutan Series

Deutan Colorblindness	Deuteranopia
CBD	Dcb
Green Colorblindness	Colorblindness, Deutan
Colorblindness, Deutan Series, Partial	Color Blindness, Red-Green

Blue Cone Monochromacy

Blue Cone Monochromatism	BCM
Cbbm	Color Blindness Blue Mono Cone Monochromatic Type
Cone Dystrophy 5, X-Linked	Colorblindness, Blue-Mono-Cone-Monochromatic Type
Achromatopsia Incomplete X-Linked	Incomplete Achromatopsia X-Linked
X-Chromosome-Linked Achromatopsia	X-Linked Achromatopsia Incomplete
Atypical X-Linked Achromatopsia	Color Blindness, Blue Monocone Monochromatic Type
S Cone Monochromacy	S Cone Monochromatism
X-Linked Incomplete Achromatopsia	Colorblindness Blue-Mono-Cone-Monochromatic Type
Cone Dystrophy 5	COD5
Cone Dystrophy 5 X-Linked	Monochromacy, Blue Cone
Cone Monochromatism	Achromatopsia Incomplete, X-Linked

Red-Green Color Blindness

Deutan Defect	Deuteranopia
Reduced Red-Green Discrimination	Color Blindness, Red-Green
Colorblindness, Partial, Deutan Series

Achromatopsia

Achm	Rod Monochromatism
Total Color Blindness	Rod Monochromacy
Monochromatism	Achromatism
Complete Or Incomplete Color Blindness	Pingelapese Blindness
Achromatopsia 1	Achromatopsia 2
Achromatopsia 3

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy	CORD2
Cone-Rod Retinal Dystrophy	Rcrd2
Cone-Rod Retinal Dystrophy 2	Crd2
Cord	Crd
Retinal Cone-Rod Dystrophy	Cone-Rod Retinal Dystrophy-2
Retinal Cone-Rod Dystrophy 2	Tapetoretinal Degeneration
Cone-Rod Degeneration	Cone Rod Dystrophy
Dystrophy, Cone-Rod	Dystrophy, Cone-Rod, Type 2
Retinitis Pigmentosa	Retinitis Pigmentosa 2
Progressive Cone-Rod Dystrophy

Bornholm Eye Disease

BED	Myopia, High, With Nonprogressive Cone Dysfunction
X-Linked Cone Dysfunction Syndrome With Myopia

Cone Dystrophy

Retinal Cone Dystrophy	Dystrophy, Cone
Cone Dystrophy 3

Color Blindness

Color Vision Defect	Blindness Color
Colour Blindness	Colour Vision Deficiency
Color Vision Deficiency	Color Vision Defects
Defective Color Vision	Vision Defect, Color
Color-Vision Disease	Dyschromatopsia

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS09796	OPN1MW Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	OPN1MW	MGD	MGI:1097692
Rattus norvegicus	OPN1MW	RGD	RGD:620978

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站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

OPN1MW - opsin 1, medium wave sensitive Gene

关于 OPN1MW

功能概要

OPN1MW 基因产物(1)

OPN1MW 蛋白结构

关联疾病

直系同源

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OPN1MW - opsin 1, medium wave sensitive Gene

关于 OPN1MW

功能概要

OPN1MW 基因产物(1)

OPN1MW 蛋白结构

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

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